3.4.21.45: complement factor I
This is an abbreviated version!
For detailed information about complement factor I, go to the full flat file.
Word Map on EC 3.4.21.45
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3.4.21.45
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hemolytic
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convertase
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macular
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properdin
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uremic
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cell-bound
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c3d
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fluid-phase
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glomerulonephritis
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complement-mediated
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opsonization
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medicine
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i-mediated
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eculizumab
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alpha\'-chain
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c4-binding
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c4bp
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microangiopathic
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opsonin
- 3.4.21.45
-
hemolytic
-
convertase
-
macular
- properdin
-
uremic
-
cell-bound
- c3d
-
fluid-phase
- glomerulonephritis
-
complement-mediated
-
opsonization
- medicine
-
i-mediated
- eculizumab
-
alpha\'-chain
-
c4-binding
- c4bp
-
microangiopathic
-
opsonin
Reaction
Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage =
Synonyms
C3b inactivator, C3b/C4b inactivator, C3bINA, CFI, complement C3b inactivator, complement C3b/C4b inactivator, complement C4b inactivator, complement C4bi, complement compoment C3b inactivator, complement factor I, complement inhibitor factor I, complement regulator factor I, conglutinogen-activating factor C, factor I, factor I-like activity, fI, GcIf-1, GcIf-2, GcIf-3, GcIf-4, IF, plasma protease factor I, serine protease Factor I
ECTree
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Activating Compound
Activating Compound on EC 3.4.21.45 - complement factor I
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C3b receptor
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obligate cofactor for factor I-mediated cleavage of cell bound C3bi
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C4-binding protein
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C4-binding protein or C4bC3bINACo required for cleavage of C4b
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purification of the pig analogue of human membrane cofactor protein, CD46/MCP, which has cofactor activity for cleavage of human and pig C3b
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JM4C8-Ag
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purification of the pig analogue of human membrane cofactor protein, CD46/MCP, which has cofactor activity for cleavage of human and pig C3b
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additional information
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Nipah virus-dependent inactivation of C3b only occurs with the cofactors factor H and soluble CR1 but not with CD46 in vitro
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