3.4.21.42: complement subcomponent C1s
This is an abbreviated version!
For detailed information about complement subcomponent C1s, go to the full flat file.
Word Map on EC 3.4.21.42
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3.4.21.42
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angioedema
-
hereditary
-
lectin
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c1-inh
-
edema
-
swell
-
mannose-binding
-
masp-1
-
mannan-binding
-
coagulation
-
kallikrein
-
airway
-
prophylaxis
-
abdominal
-
bradykinin
-
life-threatening
-
laryngeal
-
angioneurotic
-
lectin-associated
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c1-inhibitor
-
danazol
-
prophylactic
-
ficolins
-
plasma-derived
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urticaria
-
icatibant
-
antithrombin
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submucosal
-
kinin
-
fibrinolysis
-
larynx
-
kallikrein-kinin
-
asphyxiation
-
antifibrinolytic
-
prekallikrein
-
2-antiplasmin
-
ecallantide
-
2-macroglobulin
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tranexamic
-
kininogens
-
antihistamine
-
pharmacology
-
bradykinin-mediated
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serping1
-
collectins
-
behring
-
c4d
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medicine
-
collagen-like
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drug development
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tracheotomy
-
fibrinogen-like
-
stanozolol
- 3.4.21.42
- angioedema
- hereditary
- lectin
-
c1-inh
- edema
-
swell
-
mannose-binding
- masp-1
-
mannan-binding
-
coagulation
- kallikrein
-
airway
-
prophylaxis
- abdominal
- bradykinin
-
life-threatening
- laryngeal
-
angioneurotic
-
lectin-associated
- c1-inhibitor
- danazol
-
prophylactic
- ficolins
-
plasma-derived
- urticaria
- icatibant
- antithrombin
-
submucosal
- kinin
-
fibrinolysis
- larynx
-
kallikrein-kinin
-
asphyxiation
-
antifibrinolytic
- prekallikrein
-
2-antiplasmin
- ecallantide
-
2-macroglobulin
-
tranexamic
- kininogens
-
antihistamine
- pharmacology
-
bradykinin-mediated
-
serping1
-
collectins
-
behring
- c4d
- medicine
-
collagen-like
- drug development
-
tracheotomy
-
fibrinogen-like
-
stanozolol
Reaction
Cleavage of Arg-/-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-/-Lys bond in complement component C2 to form C2a and C2b: the "classical" pathway C3 convertase =
Synonyms
activated complement C1s, C1 esterase, C1-esterase, C1g, C1s, C1s protease, C1s serine protease, complement 1s, complement C.hivin. 1s, complement C1s, complement C1s, activated, complement component 1 s, complement component 1 subcomponent s, complement component C1s, complement protease, complement protease C1s, complement subcomponent 1s, complement subcomponent C1sbar, esterase, C1, mannan-binding lectin-associated serine protease-2, MASP-2, MBL-associated serine protease-2, multiprotein complex C1, protease C1s, serine protease C1s
ECTree
3.4.21.42 complement subcomponent C1sAdvanced search results
results (
results (Crystallization
Crystallization on EC 3.4.21.42 - complement subcomponent C1s
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CRYSTALLIZATION (Commentary) 
ORGANISM
UNIPROT
LITERATURE
complex between the CUB1-EGF-CUB2 domains of C1r and C1s, sitting drop vapor diffusion method, in imidazole buffer at pH 8.0 with PEG 8000 as the precipitant
crystal structure of of a catalytic fragment comprising the second complement control protein (CCP2) module and the chymotrypsin-like serine protease domain determined and refined to 1.7 A resolution
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crystallization of the whole C1 complex formed by C1q and 2 copies of each protease C1r and C1s
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in the absence of collagen peptide, C1s crystallizes to form a tetramer, similar to the native C1r-C1s-C1r-C1s complex. The tetramer is a flat ring with an outer diameter of about 120 A. The structure is assembled from two X-shaped dimers linked via a connecting interface at the center, structure overview
