3.4.21.42: complement subcomponent C1s

This is an abbreviated version, for detailed information about complement subcomponent C1s, go to the full flat file.

Reaction

Cleavage of Arg-/-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-/-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase =

Synonyms

activated complement C1s, C1 esterase, C1-esterase, C1s, C1s protease, C1s serine protease, complement 1s, complement C.hivin. 1s, complement C1s, activated, complement component C1s, complement protease, complement protease C1s, complement subcomponent 1s, complement subcomponent C1sbar, esterase, C1, mannan-binding lectin-associated serine protease-2, MASP-2, MBL-associated serine protease-2, protease C1s, serine protease C1s

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.42 complement subcomponent C1s