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3.4.21.32: brachyurin

This is an abbreviated version!
For detailed information about brachyurin, go to the full flat file.

Word Map on EC 3.4.21.32

Reaction

hydrolysis of proteins, with broad specificity for peptide bonds. Native collagen is cleaved about 75% of the length of the molecule from the N-terminus. Low activity on small molecule substrates of both trypsin and chymotrypsin =

Synonyms

aspergillopeptidase C, azocollase, clostridiopeptidase A, clostridiopeptidase I, clostridiopeptidase II, CLSP, collagen peptidase, collagenase, collagenase A, collagenase MMP-1, collagenolytic protease, collagenolytic serine protease, crab protease I, crab protease II, Es-CLSP, kollaza, matrix metalloproteinase-1, matrix metalloproteinase-18, Matrix metalloproteinase-8, metallocollagenase, metalloproteinase-1, MMP-1, MMP-8, non-clip domain serine protease, nucleolysin, peptidase, clostridio-, A, protease PC, proteinase, Clostridium histolyticum, A, PtSP, PtSPH1, soycollagestin, Try4, uca pugilator collagenolytic proteinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.32 brachyurin

Reference

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Reference on EC 3.4.21.32 - brachyurin

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Welgus, H.G.; Grant, G.A.
Degradation of collagen substrates by a trypsin-like serine protease from the fiddler crab Uca pugilator
Biochemistry
22
2228-2233
1983
Leptuca pugilator
Manually annotated by BRENDA team
Grant, G.A.; Sacchettiui, J.C.; Welgus, H.G.
A collagenolytic serine protease with trypsin-like specificity from the fiddler crab Uca pugilator
Biochemistry
22
354-358
1983
Leptuca pugilator
Manually annotated by BRENDA team
Welgus, H.G.; Grant, G.A.; Jeffrey, J.J.; Eisen, A.Z.
Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with collagenous substrates
Biochemistry
21
5183-5189
1982
Leptuca pugilator
Manually annotated by BRENDA team
Grant, G.A.; Eisen, A.Z.; Bradshaw, R.A.
Collagenolytic protease from fiddler crab (Uca pugilator)
Methods Enzymol.
80
722-734
1981
Leptuca pugilator
-
Manually annotated by BRENDA team
Grant, G.A.; Eisen, A.Z.
Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with noncollagenous substrates
Biochemistry
19
6089-6095
1980
Leptuca pugilator
Manually annotated by BRENDA team
Grant, G.A.; Henderson, K.O.; Eisen, A.Z.; Bradshaw, R.A.
Amino acid sequence of a collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator
Biochemistry
19
4653-4659
1980
Leptuca pugilator
Manually annotated by BRENDA team
Eisen, A.Z.; Henderson, K.O.; Jeffrey, J.J.; Bradshaw, R.A.
A collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator. Purification and properties
Biochemistry
12
1814-1822
1973
Leptuca pugilator
Manually annotated by BRENDA team
Eisen, A.Z.; Jeffrey, J.J.
An extractable collagenase from crustacean hepatopancreas
Biochim. Biophys. Acta
191
517-526
1969
Leptuca pugilator
Manually annotated by BRENDA team
Kristjansson, M.M.; Gudmundsdottir, S.; Fox, J.W.; Bjarnason, J.B.
Characterization of a collagenolytic serine proteinase from the Atlantic cod (Gadus morhua)
Comp. Biochem. Physiol. B
110
707-717
1995
Gadus morhua
Manually annotated by BRENDA team
Roy, P.; Colas, B.; Durand, P.
Purification, kinetical and molecular characterizations of a serine collagenolytic protease from greenshore crag (Carcinus maenas) digestive gland
Comp. Biochem. Physiol. B
115
87-95
1996
Carcinus maenas
Manually annotated by BRENDA team
Sellos, D.; van Wormhoudt, A.
Polymorphism and evolution of collagenolytic serine protease genes in crustaceans
Biochim. Biophys. Acta
1432
419-424
1999
Penaeus vannamei
Manually annotated by BRENDA team
Tsu, C.A.; Perona, J.J.; Schellenberger, V.; Turck, C.W.; Craik, C.S.
The substrate specificity of Uca pugilator collagenolytic serine protease 1 correlates with the bovine type I collagen cleavage sites
J. Biol. Chem.
269
19565-19572
1994
Leptuca pugilator
Manually annotated by BRENDA team
Tsu, C.A.; Craik, C.S.
Substrate recognition by recombinant serine collagenase 1 from Uca pugilator
J. Biol. Chem.
271
11563-11570
1996
Leptuca pugilator
Manually annotated by BRENDA team
Klimova, O.A.; Borukhov, S.I.; Solovyeva, N.I.; Balevskaya, T.O.; Strongin, A.Y.
The isolation and properties of collagenolytic proteases from crab hepatopancreas
Biochem. Biophys. Res. Commun.
166
1411-1420
1990
Paralithodes camtschaticus
Manually annotated by BRENDA team
Sakharov, I.Y.; Litvin, F.E
Artyukov, A.A.: Purification and characterization of two serine collagenolytic proteases from crab Paralithodes camtschatica
Comp. Biochem. Physiol. B
108
561-568
1994
Paralithodes camtschaticus
Manually annotated by BRENDA team
Lu, P.J.; Liu, H.C.; Tsai, I.H.
The midgut trypsins of shrimp (Penaeus monodon)
Biol. Chem.
371
851-859
1990
Penaeus monodon
Manually annotated by BRENDA team
Kim, S.K.; Park, P.J.; Kim, J.B.; Shahidi, F.
Purification and characterization of a collagenolytic protease from the filefish, Novoden modestrus
J. Biochem. Mol. Biol.
35
165-171
2002
Novoden modestrus
Manually annotated by BRENDA team
Rudenskaya, G.N.; Kislitsin, Y.A.; Rebrikov, D.V.
Collagenolytic serine protease PC and trypsin PC from king crab Paralithodes camtschaticus: cDNA cloning and primary structure of the enzymes
BMC Struct. Biol.
4
2-2
2004
Paralithodes camtschaticus (Q8WR11), Paralithodes camtschaticus
Manually annotated by BRENDA team
Perera, E.; Pons, T.; Hernandez, D.; Moyano, F.J.; Martinez-Rodriguez, G.; Mancera, J.M.
New members of the brachyurins family in lobster include a trypsin-like enzyme with amino acid substitutions in the substrate-binding pocket
FEBS J.
277
3489-3501
2010
Panulirus argus
Manually annotated by BRENDA team
Li, Q.; Cui, Z.; Liu, Y.; Wang, S.; Song, C.
Identification and characterization of two novel types of non-clip domain serine proteases (PtSP and PtSPH1) from cDNA haemocytes library of swimming crab Portunus trituberculatus
Fish Shellfish Immunol.
32
683-692
2012
Portunus trituberculatus (H8Y6I5), Portunus trituberculatus (H8Y6I6), Portunus trituberculatus
Manually annotated by BRENDA team
Yang, Q.Z.; Yang, Z.J.; Zhang, Y.; Li, X.L.; Zhang, W.
Molecular characteristic and expression analysis of collagenolytic serine protease from the Chinese mitten crab Eriocheir sinensis with defense response to Vibrio anguillarum challenge
Genet. Mol. Res.
13
3885-3894
2014
Eriocheir sinensis (I6LWU3), Eriocheir sinensis
Manually annotated by BRENDA team