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3.4.21.25: cucumisin

This is an abbreviated version!
For detailed information about cucumisin, go to the full flat file.

Word Map on EC 3.4.21.25

Reaction

hydrolysis of proteins with broad specificity =

Synonyms

Cuc m 1, cucumisin, cucumisin homologue, More, protC1, protease C1, religiosin C, soybean protease C1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.25 cucumisin

pH Range

pH Range on EC 3.4.21.25 - cucumisin

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3 - 11
-
pH 3: below 5% of the maximal activity, pH 11: 15% of the maximal activity
3.5 - 11.5
-
the enzyme retains more than 80% of activity from pH 3.5 to 11.5. No activity is observed at or below pH 2.0
3.5 - 7
-
activity known to decrease precipitously at pH values above the optimum pH range between 3.5 and 4.5, 10-20% activity retained at pH 6 and up to 10% activity retained at pH 7.0
4 - 12
-
pH 4: 50% of the maximal activity, pH 12: 10% of the maximal activity
5.8 - 11
-
pH 5.8: less than 15% of the maximal activity, pH 11: 80% of the maximal activity
7 - 11
-
the enzyme retains more than 80% proteolytic activity in the range of pH 7.0-11.0
8 - 11.5
-
50% of the maximal activity at pH 8 and pH 11.5
additional information
-
the 67000 Da native enzyme is more stable at acidic pH than the 54000 Da proteinase