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3.4.21.21: coagulation factor VIIa

This is an abbreviated version!
For detailed information about coagulation factor VIIa, go to the full flat file.

Word Map on EC 3.4.21.21

Reaction

Selective cleavage of Arg-/-Ile bond in factor X to form factor Xa =

Synonyms

activated blood coagulation factor VII, activated coagulation factor VII, activated factor VII, blood coagulation factor VIIa, blood-coagulation factor VII, activated, blood-coagulation factor VIIa, coagulation factor VII, coagulation factor VII(a), coagulation FVII, Eptacog alfa, Factor VII, factor VIIa, factor VIIa-sTF, factor VIIa-TF, factor VIIa/tissue factor complex, FIIa, free factor VIIa, FVII, FVIIa, FVIIa-sTF, fVIIa/TF, FVIIc, human factor VIIa + TF, More, NovoSeven, procoagulant protein factor VII, recombinant factor VIIa, recombinant factor-activated VII, rFVII, rFVIIa, serine protease factor VIIa, Serum prothrombin conversion accelerator, soluble tissue factor/factor VIIa complex, sTF/VIIa, TF-FVIIa, TF/VIIa, tissue factor/factor VIIa, tissue factor/factor VIIa complex, vitamin K dependent clotting factor

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.21 coagulation factor VIIa

Activating Compound

Activating Compound on EC 3.4.21.21 - coagulation factor VIIa

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
factor Xa
-
Herpes simplex virus 1 encoded glycoprotein C
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gC, 1000fold activity-enhancing effect in the absence of tissue factor and in the presence of 5 mM Ca2+ and 0.1 mM synthetic small unilamellar vesicles composed of 75% phosphatidylcholine and 25% phosphatidylserine
-
Janus kinase 2
-
-
-
phospholipid vesicle
-
oleoyl-1,2-diacyl-sn-glycero-3-phosphocholine and dioleoyl-1,2-diacyl-sn-glycero-3-(phospho-L-serine)
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protease-activated receptor-2
-
1.5fold activity enhancement
-
tissue factor
-
tissue factor TF
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TF-induced allosteric activation of FVIIa, binding structure, overview
-
vitamin K
additional information
-