3.4.21.19: glutamyl endopeptidase

This is an abbreviated version!
For detailed information about glutamyl endopeptidase, go to the full flat file.

Reaction

Preferential cleavage: Glu-/-, Asp-/- =

Synonyms

Alcalase, BIEP, BIGEP, BL-GSE, BLase, BS-GSE, endoproteinase Glu-C, endoproteinase V8, Glu C, Glu-C, Glu-endopeptidase, Glu-specific endopeptidase, GluScoh, GluScpr, GluSE, GluSsap, GluSW, glutamate specific endopeptidase, glutamate-specific proteinase, glutamate-specific serine endopeptidase, glutamic acid-specific endopeptidase, glutamic acid-specific proteinase, glutamic-acid-specific endopeptidase, glutamyl endopeptidase, glutamyl endopeptidase 2, glutamyl endopeptidase I, glutamyl specific endopeptidase, GluV8, GSE, gseBi gene product, protease V8, proteinase, glutamate-specific, proteinase, staphylococcal serine, SG-GSE, SGPE, Sspa, staphylococcal serine proteinase, V8 protease, V8 proteinase, V8-GSE, V8-protease, VSPase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.19 glutamyl endopeptidase

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Results	in table
5	Activating Compound
145	AA Sequence
9	Application
2	CAS Registry Number
19	Cloned(Commentary)
5	Crystallization (Commentary)
2	General Stability
32	Inhibitors
1	kcat/KM [mM/s]
38	KM Value [mM]
19	Localization
10	Metals/Ions
19	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
165	Organism
19	PDB ID
31	pH Optimum
2	pH Range
3	pH Stability
2	pI Value
4	Posttranslational Modification
40	Protein Variants
22	Purification (Commentary)
8	Reaction
4	Reaction Type
82	Reference
1	Renatured (Commentary)
6	Source Tissue
13	Specific Activity [micromol/min/mg]
3	Storage Stability
226	Substrates and Products (Substrate)
22	Subunits
102	Synonyms
19	Temperature Optimum [°C]
8	Temperature Stability [°C]
32	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.21.19 - glutamyl endopeptidase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

Alcalase

Bacillus licheniformis

-

commercial preparation containing subtilisin and glutamyl endopeptidase activities

731846, 731853

BIEP

Bacillus intermedius

-

-

650241

BIGEP

Bacillus intermedius

Q9EXR9

-

694951

BL-GSE

Bacillus licheniformis

-

-

650308, 653874

BLase

-

-

-

-

BS-GSE

Bacillus subtilis

-

-

653874

endoproteinase Glu-C

3 entries

endoproteinase V8

Staphylococcus aureus

-

-

731679

Glu C

Staphylococcus aureus

-

-

708488

Glu-C

Staphylococcus aureus

-

-

708886

Glu-endopeptidase

Bacillus intermedius

-

-

650241

Glu-specific endopeptidase

Bacillus licheniformis

-

-

650308

GluScoh

2 entries

GluScpr

2 entries

GluSE

4 entries

GluSsap

Staphylococcus saprophyticus

-

-

717307

GluSW

2 entries

glutamate specific endopeptidase

-

-

-

-

glutamate-specific proteinase

-

-

-

-

glutamate-specific serine endopeptidase

2 entries

glutamic acid-specific endopeptidase

5 entries

glutamic acid-specific proteinase

-

-

-

-

glutamic-acid-specific endopeptidase

-

-

-

-

glutamyl endopeptidase

8 entries

glutamyl endopeptidase 2

2 entries

glutamyl endopeptidase I

2 entries

glutamyl specific endopeptidase

Bacillus intermedius

-

-

650241

GluV8

3 entries

GSE

2 entries

gseBi gene product

2 entries

protease V8

-

-

-

-

proteinase, glutamate-specific

-

-

-

-

proteinase, staphylococcal serine

-

-

-

-

SG-GSE

Streptomyces griseus

-

-

653874

SGPE

-

-

-

-

Sspa

2 entries

staphylococcal serine proteinase

-

-

-

-

V8 protease

6 entries

V8 proteinase

2 entries

V8-GSE

2 entries

V8-protease

Staphylococcus aureus

-

-

707505, 708626

VSPase

2 entries

endoproteinase Glu-C

-

-

-

-

endoproteinase Glu-C

Staphylococcus aureus

-

-

707891, 708886, 710230, 710530

endoproteinase Glu-C

Staphylococcus aureus V8

-

-

-

GluScoh

Staphylococcus cohnii subsp. cohnii

-

-

717307

GluScoh

Staphylococcus cohnii subsp. cohnii GTC 248

-

-

-

GluScpr

Staphylococcus caprae

-

-

717307

GluScpr

Staphylococcus caprae GTC 378

-

-

-

GluSE

Staphylococcus epidermidis

-

-

690412, 691158, 717307

GluSE

Staphylococcus epidermidis

-

enzyme consists of 282 amino acids, composed of a preprosequence (Met1-Ser66) and a mature part (Val67-Gln282)

679805

GluSE

Staphylococcus epidermidis

P0C0Q1

-

691149

GluSE

Staphylococcus epidermidis ATCC 14990

-

-

-

GluSW

Staphylococcus warneri

-

-

690412, 691158

GluSW

Staphylococcus warneri JCM 2415

-

-

-

glutamate-specific serine endopeptidase

Staphylococcus aureus

-

-

717680

glutamate-specific serine endopeptidase

Staphylococcus aureus C-66

-

-

-

glutamic acid-specific endopeptidase

Bacillus licheniformis

-

-

653874

glutamic acid-specific endopeptidase

Bacillus subtilis

-

-

653874

glutamic acid-specific endopeptidase

Staphylococcus aureus

-

-

653874

glutamic acid-specific endopeptidase

Staphylococcus aureus V8

-

-

-

glutamic acid-specific endopeptidase

Streptomyces griseus

-

-

653874

glutamyl endopeptidase

Bacillus intermedius

Q9EXR9

-

694951

glutamyl endopeptidase

Staphylococcus aureus

-

-

691158, 731679

glutamyl endopeptidase

Staphylococcus aureus

Q2FZL2

-

753799

glutamyl endopeptidase

Staphylococcus aureus NCTC 8325

Q2FZL2

-

-

glutamyl endopeptidase

Staphylococcus epidermidis

-

-

690412, 691158

glutamyl endopeptidase

Staphylococcus epidermidis

P0C0Q1

-

691149

glutamyl endopeptidase

Staphylococcus warneri

-

-

690412, 691158

glutamyl endopeptidase

Staphylococcus warneri JCM 2415

-

-

-

glutamyl endopeptidase 2

Bacillus intermedius

-

-

650274

glutamyl endopeptidase 2

Bacillus intermedius Mrz 19

-

-

-

glutamyl endopeptidase I

Staphylococcus aureus

-

-

690412

glutamyl endopeptidase I

Staphylococcus aureus V8

-

-

-

GluV8

Staphylococcus aureus

-

-

679805, 690412, 691158, 717307

GluV8

Staphylococcus aureus ATCC 25923

-

-

-

GluV8

Staphylococcus aureus V8

-

-

-

GSE

-

-

-

-

GSE

Thermoactinomyces sp. CDF

-

-

752559

gseBi gene product

Bacillus intermedius

-

-

681809

gseBi gene product

Bacillus intermedius

Q9EXR9

-

681845

Sspa

Staphylococcus aureus

Q2FZL2

-

753799

Sspa

Staphylococcus aureus NCTC 8325

Q2FZL2

-

-

V8 protease

Staphylococcus aureus

-

-

649239, 650308, 653793, 653874, 690412, 707448, 707891, 708488, 709490, 710530

V8 protease

Staphylococcus aureus

-

member of the glutamyl endopeptidase I family, protein of 336 amino acids that includes a prepropeptide consisting of 68 residues (Met1-Asn68) and a C-terminal tail of 52 residues consisting of a 12fold repeat of the tripeptide Pro-Asp/Asn-Asn, prosegment is essential for the suppression of proteolytic activity, as well as for the correct folding of GluV8, indicating its role as an intramolecular chaperone

679805

V8 protease

Staphylococcus aureus

Q2FZL2

-

753799

V8 protease

Staphylococcus aureus NCTC 8325

Q2FZL2

-

-

V8 protease

Staphylococcus aureus V8

-

-

-

V8 protease

Staphylococcus aureus Wood 46

-

-

-

V8 proteinase

-

-

-

-

V8 proteinase

Staphylococcus aureus

-

-

709024, 710230

V8-GSE

Staphylococcus aureus

-

-

653874

V8-GSE

Staphylococcus aureus V8

-

-

-

VSPase

Staphylococcus aureus

-

-

717680

VSPase

Staphylococcus aureus C-66

-

-

-