Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.21.121: Lys-Lys/Arg-Xaa endopeptidase

This is an abbreviated version!
For detailed information about Lys-Lys/Arg-Xaa endopeptidase, go to the full flat file.

Reaction

Cleavage of -Lys-Lys-/- and -Lys-Arg-/- bonds. =

Synonyms

ASP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.121 Lys-Lys/Arg-Xaa endopeptidase

Substrates Products

Substrates Products on EC 3.4.21.121 - Lys-Lys/Arg-Xaa endopeptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Ac-Asp-Glu-Val-Asp-4-methylcoumaryl-7-amide + H2O
Ac-Asp-Glu-Val-Asp + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 0.4 nM product per min
-
?
Boc-Arg-Val-Arg-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
-
-
?
Boc-Asp(OBzl)-Pro-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Asp(OBzl)-Pro-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 2.0 nM product per min
-
?
Boc-Glu(OBzl)-Ala-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Glu(OBzl)-Ala-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.8 nM product per min
-
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
show the reaction diagram
Boc-Gly-Arg-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Gly-Arg-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.0 nM product per min
-
?
Boc-Gly-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
-
-
?
Boc-Ile-Glu-Gly-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Ile-Glu-Gly-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 64 nM product per min
-
?
Boc-Leu-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Lys-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 7.0 nM product per min
-
?
Boc-Leu-Ser-Thr-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Ser-Thr-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 45 nM product per min
-
?
Boc-Leu-Thr-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Thr-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.5 nM product per min
-
?
Boc-Phe-Ser-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Phe-Ser-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 2.2 nM product per min
-
?
Boc-Val-Leu-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Val-Leu-Lys + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.3 nM product per min
-
?
complement component C5 + H2O
complement component C5a + ?
show the reaction diagram
-
-
-
?
Fibrinogen + H2O
?
show the reaction diagram
-
-
-
?
Gly-Pro-4-methylcoumaryl-7-amide + H2O
Gly-Pro + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 0.4 nM product per min
-
?
prekallikrein + H2O
?
show the reaction diagram
-
-
-
?
prothrombin + H2O
alpha-thrombin + prothrombin fragments
show the reaction diagram
-
-
-
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
Suc(OMe)-Ala-Ala-Pro-Val-4-methylcoumaryl-7-amide + H2O
Suc(OMe)-Ala-Ala-Pro-Val + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.2 nM product per min
-
?
Suc-Ala-Ala-Pro-Phe-4-methylcoumaryl-7-amide + H2O
Suc-Ala-Ala-Pro-Phe + 7-amino-4-methylcoumarin
show the reaction diagram
-
release of 1.8 nM product per min
-
?