3.4.21.119: kallikrein 13

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For detailed information about kallikrein 13, go to the full flat file.

Reaction

Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin =

Synonyms

GK-13, glandular kallikrein 13, glandular kallikrein K13, hK13, K13, kallikrein-related peptidase 13, KLK13, MGK-13, mK13, More, PRECE, prorenin converting enzyme, prorenin-converting enzyme, S01.306, tissue kallikrein

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.119 kallikrein 13

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Results	in table
5	Activating Compound
2	AA Sequence
11	Application
2	CAS Registry Number
6	Cloned(Commentary)
1	Crystallization (Commentary)
98	Disease/ Diagnostics
3	Expression
4	General Information
1	General Stability
2	IC50 Value
12	Inhibitors
8	kcat/KM [mM/s]
8	KM Value [mM]
6	Localization
1	Metals/Ions
7	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
23	Organism
5	pH Optimum
1	pI Value
2	Posttranslational Modification
1	Protein Variants
5	Purification (Commentary)
7	Reaction
1	Reaction Type
23	Reference
79	Source Tissue
1	Specific Activity [micromol/min/mg]
49	Substrates and Products (Substrate)
7	Subunits
28	Synonyms
3	Temperature Optimum [°C]
8	Turnover Number [1/s]

Sequence

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Sequence on EC 3.4.21.119 - kallikrein 13

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UNIPROT

ENTRY NAME

ORGANISM

NO. OF AA

NO. OF TRANSM. HELICES

MOLECULAR WEIGHT[Da]

SOURCE

SEQUENCE

LOCALIZATION PREDICTIONThe reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).

P36368 pBLAST

EGFB2_MOUSE

Mus musculus

261

0

28689

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

Q9UKR3 pBLAST

KLK13_HUMAN

Homo sapiens

277

0

30570

Swiss-Prot

Show Sequence

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