3.4.21.119: kallikrein 13

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For detailed information about kallikrein 13, go to the full flat file.

Word Map on EC 3.4.21.119

3.4.21.119

kallikreins

prorenins

submandibular

medicine

trypsin-like

endoproteolytic

diagnostics

renin-angiotensin

analysis

Reaction

Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin =

Synonyms

GK-13, glandular kallikrein 13, glandular kallikrein K13, hK13, K13, kallikrein-related peptidase 13, KLK13, MGK-13, mK13, More, PRECE, prorenin converting enzyme, prorenin-converting enzyme, S01.306, tissue kallikrein

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.119 kallikrein 13

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Results	in table
5	Activating Compound
2	AA Sequence
11	Application
2	CAS Registry Number
6	Cloned(Commentary)
1	Crystallization (Commentary)
98	Disease/ Diagnostics
3	Expression
4	General Information
1	General Stability
2	IC50 Value
12	Inhibitors
8	kcat/KM [mM/s]
8	KM Value [mM]
6	Localization
1	Metals/Ions
7	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
23	Organism
5	pH Optimum
1	pI Value
2	Posttranslational Modification
1	Protein Variants
5	Purification (Commentary)
7	Reaction
1	Reaction Type
23	Reference
79	Source Tissue
1	Specific Activity [micromol/min/mg]
49	Substrates and Products (Substrate)
7	Subunits
28	Synonyms
3	Temperature Optimum [°C]
8	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.4.21.119 - kallikrein 13

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polypeptide + H2O

peptides

5 entries

Prorenin + H2O

Renin + ?

3 entries

additional information

Homo sapiens

enzyme is involved in tissue remodeling and/or tumor invasion and metastasis

667393