3.4.21.118: kallikrein 8
This is an abbreviated version!
For detailed information about kallikrein 8, go to the full flat file.
Word Map on EC 3.4.21.118
-
3.4.21.118
-
kallikreins
-
klk8
-
melanopsin
-
desquamation
-
photopigment
-
iprgcs
-
non-visual
-
peropsin
-
medicine
-
biotechnology
-
molecular biology
-
pharmacology
-
analysis
- 3.4.21.118
- kallikreins
- klk8
- melanopsin
-
desquamation
-
photopigment
-
iprgcs
-
non-visual
-
peropsin
- medicine
- biotechnology
- molecular biology
- pharmacology
- analysis
Reaction
cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys =
Synonyms
Alzheimers associated protease, brain serine protease 1, GK-8, hK8, kallikrein 8, kallikrein 8 protease, kallikrein-8, kallikrein-related peptidase, kallikrein-related peptidase 8, kallikrein-related peptidase-8, KLK8, KRP/hK8, mK8, neuropsin, NP, ovasin, P1 kallikrein, PRSS19, RGK-8, S01.244, TADG-14, TADG14, tissue kallikrein, type I neuropsin, type II neuropsin
ECTree
Advanced search results
Source Tissue
Source Tissue on EC 3.4.21.118 - kallikrein 8
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
KLK8 expression is upregulated in left ventricle of cardiac hypertrophy models
-
oligodendrocytes only express Klk8 mRNA after injury to the central nervous system
low activity in nonpregnant uteri, increased activity in pregnant uteri, highest at midgestational period
additional information
-
the epidermis of the skin is one of the tissues that exhibits a high level of KLK8 expression
-
hK8 and serpinB6 are co-expressed in differentiated primary human keratinocytes
-
interaction between murine serpinB6 and mK8 is at least 10fold faster than that observed for serpinB6 and hK8
expression of Klk8 in the imiquimod-treated skin is significantly higher than that in untreated skin
-
KRP/hK8 present in lung small cell carcinoma and carcinoid tumour cell
additional information
-
KLK8 is not secreted by human melanocytes or dermal fibroblasts