3.4.21.118: kallikrein 8
This is an abbreviated version!
For detailed information about kallikrein 8, go to the full flat file.
Word Map on EC 3.4.21.118
-
3.4.21.118
-
kallikreins
-
klk8
-
melanopsin
-
desquamation
-
photopigment
-
iprgcs
-
non-visual
-
peropsin
-
medicine
-
biotechnology
-
molecular biology
-
pharmacology
-
analysis
- 3.4.21.118
- kallikreins
- klk8
- melanopsin
-
desquamation
-
photopigment
-
iprgcs
-
non-visual
-
peropsin
- medicine
- biotechnology
- molecular biology
- pharmacology
- analysis
Reaction
cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys =
Synonyms
Alzheimers associated protease, brain serine protease 1, GK-8, hK8, kallikrein 8, kallikrein 8 protease, kallikrein-8, kallikrein-related peptidase, kallikrein-related peptidase 8, kallikrein-related peptidase-8, KLK8, KRP/hK8, mK8, neuropsin, NP, ovasin, P1 kallikrein, PRSS19, RGK-8, S01.244, TADG-14, TADG14, tissue kallikrein, type I neuropsin, type II neuropsin
ECTree
Advanced search results
Localization
Localization on EC 3.4.21.118 - kallikrein 8
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
-
KRP/hK8 is nuclear in glial cells of the brain, in myoepithelial cells of the submandibular gland and in the adenocarcinoma
-
distributed in keratinocytes in the stratum spinosum and granulosum
-
KRP/hK8 is cytoplasmic in brain, lung and submandibular gland and is present in the cytoplasm of squamous cell carcinoma, small cell carcinoma and carcinoid tumour. Absent from cytoplasm of tumour cells of adenocarcinoma
disruption of loop C and the kallikrein loop enhances the regulated secretion, no loop disruption does lead to inhibition of secretion
-