3.4.21.118: kallikrein 8

This is an abbreviated version!
For detailed information about kallikrein 8, go to the full flat file.

Reaction

cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys =

Synonyms

Alzheimers associated protease, brain serine protease 1, GK-8, hK8, kallikrein 8, kallikrein 8 protease, kallikrein-8, kallikrein-related peptidase, kallikrein-related peptidase 8, kallikrein-related peptidase-8, KLK8, KRP/hK8, mK8, neuropsin, NP, ovasin, P1 kallikrein, PRSS19, RGK-8, S01.244, TADG-14, TADG14, tissue kallikrein, type I neuropsin, type II neuropsin

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.118 kallikrein 8

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
6	Activating Compound
7	AA Sequence
14	Application
2	CAS Registry Number
13	Cloned(Commentary)
2	Crystallization (Commentary)
352	Disease/ Diagnostics
7	Expression
9	General Information
1	General Stability
45	Inhibitors
11	kcat/KM [mM/s]
1	Ki Value [mM]
28	KM Value [mM]
11	Localization
6	Metals/Ions
10	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
198	Organism
5	PDB ID
9	pH Optimum
3	pH Range
8	Posttranslational Modification
17	Protein Variants
7	Purification (Commentary)
11	Reaction
2	Reaction Type
51	Reference
88	Source Tissue
3	Specific Activity [micromol/min/mg]
3	Storage Stability
116	Substrates and Products (Substrate)
8	Subunits
70	Synonyms
6	Temperature Optimum [°C]
21	Turnover Number [1/s]

General Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Stability on EC 3.4.21.118 - kallikrein 8

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to General Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

KLK8 displays 2.5fold higher activity in 100 mM sodium phosphate buffer than in 50 mM Tris-HCl buffer

Homo sapiens

-

717863