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3.4.21.115: infectious pancreatic necrosis birnavirus Vp4 peptidase

This is an abbreviated version!
For detailed information about infectious pancreatic necrosis birnavirus Vp4 peptidase, go to the full flat file.

Word Map on EC 3.4.21.115

Reaction

cleaves the (Ser/Thr)-Xaa-Ala-/-(Ser/Ala)-Gly motif in the polyprotein NH2-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions =

Synonyms

avian infectious busrsal disease birnavirus Vp4 endopeptidase, blotched snakehead birnavirus endopeptidase, Drosophila X virus Vp4 protease, equine arterivirus serine peptidase, infectious pancreatic necrosis birnavirus Vp4 protease, NS, NS protease, S50.001, VP4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase

Reference

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Reference on EC 3.4.21.115 - infectious pancreatic necrosis birnavirus Vp4 peptidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Petit, S.; Lejal, N.; Huet, J.C.; Delmas, B.
Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus
J. Virol.
74
2057-2066
2000
infectious pancreatic necrosis virus (Q703G9)
Manually annotated by BRENDA team
Lee, J.; Feldman, A.R.; Delmas, B.; Paetzel, M.
Expression, purification and crystallization of a birnavirus-encoded protease, VP4, from blotched snakehead virus (BSNV)
Acta Crystallogr. Sect. F
F62
353-356
2006
Blotched snakehead virus
Manually annotated by BRENDA team
Gorbalenya, A.E.; Mundt, E.
Birnavirus VP4 processing endopeptidase
Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. )Academic Press
2
1995-1998
2004
Infectious bursal disease virus, infectious pancreatic necrosis virus, Blotched snakehead virus, Drosophila X virus
-
Manually annotated by BRENDA team
Feldman, A.R.; Lee, J.; Delmas, B.; Paetzel, M.
Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism
J. Mol. Biol.
358
1378-1389
2006
Blotched snakehead virus (Q8AZM0)
Manually annotated by BRENDA team
Manning, D.S.; Leong, J.C.
Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus
Virology
179
16-25
1990
infectious pancreatic necrosis virus
Manually annotated by BRENDA team
Imajoh, M.; Goto, T.; Oshima, S.
Characterization of cleavage sites and protease activity in the polyprotein precursor of Japanese marine aquabirnavirus and expression analysis of generated proteins by a VP4 protease activity in four distinct cell lines
Arch. Virol.
152
1103-1114
2007
marine birnavirus
Manually annotated by BRENDA team
Lee, J.; Feldman, A.R.; Delmas, B.; Paetzel, M.
Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction
J. Biol. Chem.
282
24928-24937
2007
infectious pancreatic necrosis virus (Q703G9)
Manually annotated by BRENDA team
Chung, I.Y.; Paetzel, M.
Crystal structure of a viral protease intramolecular acyl-enzyme complex: insights into cis-cleavage at the VP4/VP3 junction of Tellina birnavirus
J. Biol. Chem.
286
12475-12482
2011
Tellina virus 1 (Q2PBR5)
Manually annotated by BRENDA team