3.4.21.110: C5a peptidase

This is an abbreviated version!
For detailed information about C5a peptidase, go to the full flat file.

Reaction

the primary cleavage site is at His67-/-Lys68 in human C5a with a minor secondary cleavage site at Ala58-/-Ser59 =

Synonyms

C5a peptidase, GBS, GBS C5a peptidase, S08.020, SCFI, SCPA, ScpB, scpI, SCPZ, SEZ C5a peptidase, streptococcal chemotactic factor inactivator, surface-bound C5a peptidase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.110 C5a peptidase

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Results	in table
1	Activating Compound
679	AA Sequence
18	Application
1	CAS Registry Number
11	Cloned(Commentary)
2	Crystallization (Commentary)
2	Expression
5	General Information
13	Inhibitors
3	KM Value [mM]
2	Localization
1	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
30	Organism
5	PDB ID
4	pH Optimum
2	pH Range
1	Posttranslational Modification
18	Protein Variants
7	Purification (Commentary)
1	Reaction
12	Reaction Type
30	Reference
1	Specific Activity [micromol/min/mg]
2	Storage Stability
40	Substrates and Products (Substrate)
35	Synonyms
2	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
2	Turnover Number [1/s]

Organism

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Organism on EC 3.4.21.110 - C5a peptidase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Streptococcus agalactiae

2 entries

Streptococcus equi subsp. zooepidemicus

Streptococcus zooepidemicus, gene scpZ

732903

B4U2T7

UniProt

brenda

Streptococcus equi subsp. zooepidemicus MGCS10565

Streptococcus zooepidemicus, gene scpZ

732903

B4U2T7

UniProt

brenda

Streptococcus iniae

-

700885

-

-

brenda

Streptococcus pyogenes

4 entries

Streptococcus pyogenes serotype M1

-

755210

P58099

UniProt

brenda

Streptococcus pyogenes SSI-9

-

674559

-

-

brenda

Streptococcus sp.

8 entries

Streptococcus sp. COH1

group B streptococci

687071

-

-

brenda

Streptococcus agalactiae

-

708708

-

-

brenda

Streptococcus agalactiae

group B streptococcus, serotype II strain

676783

-

-

brenda

Streptococcus pyogenes

-

651137, 651472, 651482, 651484, 651655, 674559, 699571, 708708

-

-

brenda

Streptococcus pyogenes

-

755385

B6ETQ5

UniProt

brenda

Streptococcus pyogenes

group A streptococcal serotype M1 strains 90-131, 90-226 and MGAS5005, serotype M49 strain CS101

677242

-

-

brenda

Streptococcus pyogenes

wild-type and mutants that do not express the enzyme

652690

-

-

brenda

Streptococcus sp.

group A streptococci

687103

-

-

brenda

Streptococcus sp.

group A streptococcus

673974

-

-

brenda

Streptococcus sp.

group A streptococcus strain 90 226 serotype M1

673973

-

-

brenda

Streptococcus sp.

group A Streptococcus strain 90 226 serotype M1, strain Xen-20 serotype M49

673982

-

-

brenda

Streptococcus sp.

group B

717065, 717499

-

-

brenda

Streptococcus sp.

group B streptococci

684134, 684315, 687071

-

-

brenda

Streptococcus sp.

M49T14 group A streptococci

676910

-

-

brenda

Streptococcus sp.

strain 7360 group B streptococci and strain GW

671820

-

-

brenda