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3.4.21.105: rhomboid protease

This is an abbreviated version!
For detailed information about rhomboid protease, go to the full flat file.

Word Map on EC 3.4.21.105

Reaction

cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains =

Synonyms

AAR, AarA, AqRho, Derlin-1, EhROM1, GlpG, GlpP, intramembrane protease, microneme rhomboid protease, More, paGlpG, PARL, PBANKA_110650, PbROM1, Pcp1, Pcp1/Rbd1, pfROM4, presenilin associated rhomboid like protein, presenilin-associated rhomboid-like, presenilin-associated rhomboid-like protein, presenilins-associated rhomboid-like protein, PSARL, Rbd1, Rbd1p, RBL1, RBL10, RBL11, RBL12, RBL2, RBL3, RBL4, RBL5, RBL6, RBL7, RBL8, RBL9, Rhbdd1, RHBDL, RHBDL2, RHBDL4, RHDBL-2, Rho, RHO-1, rho-4, Rho-7, RhoII, Rhomboid, Rhomboid 4, rhomboid intramembrane protease, rhomboid Pcp1/Rbd1, rhomboid peptidase Pcp1, rhomboid protease, Rhomboid protease AarA, Rhomboid protease glpG, Rhomboid protease gluP, rhomboid protease Pcp1, rhomboid protease PSARL, Rhomboid protein, rhomboid protein 1, rhomboid protein 4, rhomboid pseudoprotease, rhomboid serine protease, rhomboid-1, rhomboid-1 protease, rhomboid-2, rhomboid-3, rhomboid-4, rhomboid-like protein, rhomboid-like protein 10, rhomboid-related protein 4, rhomboid-type protease Pcp1, ROM1, ROM4, ROM5, Spitz protease, TgROM1, TgROM2, TgROM3, TgROM4, TgROM5, Ygr101w, Yqgp

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.105 rhomboid protease

Cloned

Cloned on EC 3.4.21.105 - rhomboid protease

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
co-expression of Rhomboid-1 with growth factor Spitz in COS-7 cells
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DNA and amino acid sequence analysis, phylogenetic analysis, overview
expressed as a C-terminal His-tagged fusion protein in Escherichia coli BL21
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expressed in COS-1 cells as a myc-tagged fusion protein by transient transfection
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expressed in Escherichia coli as a GST-fusion protein
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expressed in Escherichia coli BL21 C43(DE3) cells
expressed in Escherichia coli C43(DE3) cells
expressed in Escherichia coli Top10 cells
expression in Escherichia coli
expression of His-tagged GlpG in Escherichia coli strain C43(DE3)
expression of N-terminally HA3-tagged ROMs
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expression of wild-type HA9-tagged ROM1 and of muant ROM1 in the parasites, repression of Tet-regulatable HA9-ROM1 expression in the presence of Atc, overview
gene aarA, DNA and amino acid sequence determination and analysis, expression of the C-terminally His-tagged AarA in Escherichia coli, expression of the tat operon is not dependent on aarA
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HEK 293 cells transfected with a FLAG-tagged PARL construct
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overexpressed in Escherichia coli BL21(DE3) as full-length, C-terminally His-tagged protein
phylogenetic analysis
recombinantly expressed in Mycobacterium bovis BCG strains using extrachromosomal vector pMV261 and integrative vector pMV361, respectively
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seven rhomboid genes
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transfection of HEK-293T cell
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transiently expressed in COS, HeLa, HEK 293, and CHO cells as a N-terminal hemagglutinin tagged fusion protein
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