3.4.21.104: mannan-binding lectin-associated serine protease-2
This is an abbreviated version!
For detailed information about mannan-binding lectin-associated serine protease-2, go to the full flat file.
Reaction
Selective cleavage after Arg223 in complement component C2 (-Ser-Leu-Gly-Arg-/-Lys-Ile-Gln-Ile) and after Arg76 in complement component C4 (-Gly-Leu-Gln-Arg-/-Ala-Leu-Glu-Ile)
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Synonyms
CCP1-CCP2-SP, Mannan-binding lectin associated serine protease-2, mannan-binding lectin-associated serine protease, mannan-binding lectin-associated serine protease 2, mannan-binding lectin-associated serine protease-2, mannose-binding lectin-associated serine protease 2, mannose-binding lectin-associated serine protease-2, mannose-binding lectin-associated-serine protease-2, Map19, MASP, MASP-2, MASP-2A, MASP-2K, MASP2, MBL-associated serine protease, MBL-associated serine protease 2, MBL-associated serine protease-2, MBL-associated-serine protease-2, MBL-MASP, MBL/ficolin-associated serine protease, MBP-associated serine protease, MBP-associated serine protease 2, MBP-associated serine protease-2, S01.229
ECTree
Synonyms
Synonyms on EC 3.4.21.104 - mannan-binding lectin-associated serine protease-2
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CCP1-CCP2-SP
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complement control protein-like domain 1-complement control protein-like domain-2-serine protease, catalytic segment of MASP-2
Mannan-binding lectin associated serine protease-2
mannan-binding lectin-associated serine protease
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mannan-binding lectin-associated serine protease 2
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mannan-binding lectin-associated serine protease-2
mannose-binding lectin-associated serine protease 2
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mannose-binding lectin-associated serine protease-2
mannose-binding lectin-associated-serine protease-2
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MASP-2A
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catalytically inactive form in which the active site serine at position 613 has been replaced by alanine
MASP-2K
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catalytically active form in which the arginine residue at the cleavage site for zymogen activation (Arg424) has been changed to a lysine residue to slow down the rate of spontaneous autoactivation during biosynthesis
MBL-associated serine protease
MBL-associated serine protease 2
MBL-associated serine protease-2
MBL-associated-serine protease-2
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MBL/ficolin-associated serine protease
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MBP-associated serine protease
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MBP-associated serine protease 2
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MBP-associated serine protease-2
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Mannan-binding lectin associated serine protease-2
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Mannan-binding lectin associated serine protease-2
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Mannan-binding lectin associated serine protease-2
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mannan-binding lectin-associated serine protease-2
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mannan-binding lectin-associated serine protease-2
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mannose-binding lectin-associated serine protease-2
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mannose-binding lectin-associated serine protease-2
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Map19
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MASP-2 exists in an alternatively spliced form, known as Map19
MASP-2
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652143, 652189, 652674, 652677, 652683, 652684, 653250, 653331, 659629, 659959, 677421, 680105, 680169, 681205, 683124, 683500, 683524, 683743, 683891, 683927, 700247, 700248, 708201, 708697, 709344, 709354, 717934, 718122, 718181
MASP-2
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MASP-2 collaborates with MASP-1 in the generation of C3 convertase
MASP-2
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protein of the lectin pathway, can autoactivate and cleaves complements C2 and C4
MASP-2
exclusively cleaves complement 4
MASP2
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MBL-associated serine protease
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MBL-associated serine protease
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MBL-associated serine protease 2
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MBL-associated serine protease 2
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MBL-associated serine protease 2
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MBL-associated serine protease-2
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MBL-associated serine protease-2
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MBL-associated serine protease-2
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MBL-associated serine protease-2
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