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3.4.21.1: chymotrypsin

This is an abbreviated version!
For detailed information about chymotrypsin, go to the full flat file.

Word Map on EC 3.4.21.1

Reaction

Preferential cleavage: Tyr-/-, Trp-/-, Phe-/-, Leu-/- =

Synonyms

4CHA, Alcalase, alpha chymar, alpha chymotrypsin, alpha-Chy, alpha-chymar ophth, alpha-chymotrypsin, alpha-chymotrypsin A, alpha-CT, avazyme, bovine alpha-chymotrypsin, caldecrin, cationic chymotrypsin, cellulomonadin, CHT, Chtp, Chtr1, Chtr2, Chtr3, Chtr4, ChTRP, CHY1, CHY20, chymar, chymotest, chymotrypsin, chymotrypsin A, chymotrypsin B, chymotrypsin C, chymotrypsin C1, chymotrypsin I, chymotrypsin II, chymotrypsin isoform Kh1, chymotrypsin isoform Kh2, chymotrypsin isoform Kh3, chymotrypsin-B, CTRA, Ctrb, EC 3.4.4.5, EC 3.4.4.6, enzeon, LBCP, lysosomal Bid cleavage protease, PEG-alpha-chymotrypsin, PEG-modified alpha-chymotrypsin, quimar, quimotrase, serine protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.1 chymotrypsin

Molecular Weight

Molecular Weight on EC 3.4.21.1 - chymotrypsin

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
18499
x * 18499, deduced from nucleotide sequence
20000
-
light scattering analysis
20100
-
SDS-PAGE, enzyme is not heat-treated prior to electrophoresis
23600
-
gel filtration
23720
x * 27000, SDS-PAGE, x * 23720, calculated
23800
-
gel filtration
24000
24061
2 * 24061, MALDI mass spectroscopy
24852
-
x * 24852, calculation from nucleotide sequence
25000
25210
-
MALDI-TOF analysis
25500
-
gel filtration
26000
26309
-
x * 26309, calculation from amino acid analysis
26990
-
x * 26990, enzyme form LCTb, SDS-PAGE
27000
28000
29000
-
x * 29000, SDS-PAGE
31000
-
SDS-PAGE
39800
-
Sephadex G-75 superfine gel chromatography
48000
chymotrypsin C1 migrates on SDS-PAGE as a very stable dimer of 48000 Da
669000
gel filtration
additional information