3.4.19.7: N-Formylmethionyl-peptidase

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For detailed information about N-Formylmethionyl-peptidase, go to the full flat file.

Reaction

release of an N-terminal, formyl-methionyl residue from a polypeptide =

Synonyms

(fMet)-releasing enzyme, Aminopeptidase, formylmethionine, Formylmethionine aminopeptidase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.19 Omega peptidases

                3.4.19.7 N-Formylmethionyl-peptidase

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Results	in table
1	CAS Registry Number
16	Inhibitors
12	KM Value [mM]
3	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	pH Range
2	Purification (Commentary)
1	Reaction
1	Reaction Type
2	Reference
3	Source Tissue
2	Specific Activity [micromol/min/mg]
15	Substrates and Products (Substrate)
1	Subunits
3	Synonyms
2	Temperature Optimum [°C]
10	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.4.19.7 - N-Formylmethionyl-peptidase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

N-Formylmethionyl oligopeptides + H2O

?

Rattus norvegicus

-

the presence of this enzyme in intestinal mucosa can prevent absorption of intact bioactive potent inflammatory N-formylmethionyl oligopeptides produced by commensal bacteria in the gut lumen

29061

-

-

?