3.4.19.15: desampylase

This is an abbreviated version!
For detailed information about desampylase, go to the full flat file.

Word Map on EC 3.4.19.15

3.4.19.15

metalloprotease

ubiquitin-like

molybdopterin

ubiquitin

volcanii

haloferax

sampylation

metalloenzyme

Reaction

an N6-[small archaeal modifier protein]-[protein]-L-lysine

Synonyms

EC 3.4.24.88, HvJAMM1, HVO_2505, JAMM protease, JAMM1

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.19 Omega peptidases

3.4.19.15 desampylase

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Results	in table
24	AA Sequence
2	Cloned(Commentary)
6	General Information
6	Inhibitors
3	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
14	Organism
1	pH Optimum
10	Protein Variants
2	Purification (Commentary)
1	Reaction
8	Reference
18	Substrates and Products (Substrate)
4	Subunits
13	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]

Inhibitors

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Inhibitors on EC 3.4.19.15 - desampylase

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1,10-phenanthroline

Haloferax volcanii

D4GTS4

inhibits at a molar ratio of inhibitor to enzyme of 50:1

730410

EDTA

2 entries

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine

Haloferax volcanii

D4GTS4

inhibits at a molar ratio of inhibitor to enzyme of 5:1. Addition of excess Zn2+ restores its activity, while addition of Fe2+, Cu2+ and Ni2+ does not reactivate the enzyme

730410

N-ethylmaleimide

Haloferax volcanii

D4GTS4

inhibits at a molar ratio of inhibitor to enzyme of 20:1

730410

additional information

2 entries