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3.4.19.14: leukotriene-C4 hydrolase

This is an abbreviated version!
For detailed information about leukotriene-C4 hydrolase, go to the full flat file.

Word Map on EC 3.4.19.14

Reaction

leukotriene C4
+
H2O
=
leukotriene D4
+
L-glutamate

Synonyms

gamma-glutamyl leukotrienase, GGL, GGT5

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.19 Omega peptidases
                3.4.19.14 leukotriene-C4 hydrolase

KM Value

KM Value on EC 3.4.19.14 - leukotriene-C4 hydrolase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0751
glutathione sulfonic acid
-
in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C
0.0022 - 0.0102
leukotriene C4
0.426
oxidized glutathione
-
in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C
0.105
reduced glutathione
-
in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C
0.0148
S-(4-nitro-benzyl)glutathione
-
in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C
0.03
S-decyl-GSH
-
in 0.1 M Tris-HCl buffer, pH 8.0, at 37°C
0.0182
S-Methylglutathione
-
in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C