3.4.19.1: acylaminoacyl-peptidase

This is an abbreviated version!
For detailed information about acylaminoacyl-peptidase, go to the full flat file.

Reaction

cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide =

Synonyms

AAP, AARE, AARE/OPH, AAREP, AcpH, acyl aminoacyl peptidase, acyl peptide hydrolase, Acyl-peptide hydrolase, acyl-peptide releasing enzyme, acylamino acid-releasing enzyme, acylamino acid-releasing enzyme/oxidized protein hydrolase, acylamino-acid-releasing enzyme, acylaminoacyl peptidase, Acylaminoacyl-peptidase, acylpeptide hydrolase, acylpeptide hydrolase/esterase, alpha-N-acylpeptide hydrolase, ApAAP, apAPH, APEH, APEH-1, apeH-2, APEH-3, APEH-3Ss, APEHs, APE_1547.1, APH, APHdr, AtAARE, BmAPH, cAARE, DNF15S2 protein, N-acylaminoacyl-peptide hydrolase, N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, OP85, PhAAP, pi-APH, PM hydrolase, PMH, SpAAP, sso2141, SSO2693, ST0779, yuxL

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.19 Omega peptidases

                3.4.19.1 acylaminoacyl-peptidase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
3067	AA Sequence
16	Application
1	CAS Registry Number
26	Cloned(Commentary)
13	Crystallization (Commentary)
420	Disease/ Diagnostics
5	Expression
50	General Information
10	General Stability
63	IC50 Value
180	Inhibitors
19	kcat/KM [mM/s]
9	Ki Value [mM]
96	KM Value [mM]
16	Localization
3	Metals/Ions
40	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
366	Organism
1	Pathway
48	PDB ID
35	pH Optimum
9	pH Range
5	pH Stability
1	pI Value
56	Protein Variants
36	Purification (Commentary)
2	Reaction
11	Reaction Type
118	Reference
1	Renatured (Commentary)
77	Source Tissue
48	Specific Activity [micromol/min/mg]
2	Storage Stability
342	Substrates and Products (Substrate)
50	Subunits
177	Synonyms
28	Temperature Optimum [°C]
6	Temperature Range [°C]
19	Temperature Stability [°C]
75	Turnover Number [1/s]

pH Range

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

pH Range on EC 3.4.19.1 - acylaminoacyl-peptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to pH Range Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 10

Sulfurisphaera tokodaii

Q973W9

inactivation of wild-type enzyme at pH 10.0

752694

5 - 8

Pyrococcus horikoshii

-

about 60% of maximal activity at pH 5 and pH 8

95261

5 - 9

Saccharolobus solfataricus

Q97VD6

more than 50% activity between pH 5.0 and 9.0

720867

5 - 9.5

Sulfurisphaera tokodaii

Q973W9

inactivation of enzyme mutants at pH 9.0-9.5

752694

5.8 - 8.8

Aeropyrum pernix

Q9YBQ2

pH 5.8: about% of maximal activity, pH 8.8: about% of maximal activity

727876

6 - 9.5

Sulfurisphaera tokodaii

Q973W9

pH 6.0: about 65% of maximal activity, pH 9.5: about 70% of maximal activity

724738

7 - 9

Homo sapiens

-

about 55% of maximal activity at pH 7 and at pH 13

95253

7.5 - 8

Saccharolobus solfataricus

Q97VD6

pH 7.5: about 55% of maximal activity, pH 8.0: about 75% of maximal activity

720867

7.5 - 9.5

Aeropyrum pernix

Q9YBQ2

pH 7.5: about 50% of maximal activity, pH 9.5: about 65% of maximal activity, wild-type enzyme

723816