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3.4.19.1: acylaminoacyl-peptidase

This is an abbreviated version!
For detailed information about acylaminoacyl-peptidase, go to the full flat file.

Word Map on EC 3.4.19.1

Reaction

cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide =

Synonyms

AAP, AARE, AARE/OPH, AAREP, AcpH, acyl aminoacyl peptidase, acyl peptide hydrolase, Acyl-peptide hydrolase, acyl-peptide releasing enzyme, acylamino acid-releasing enzyme, acylamino acid-releasing enzyme/oxidized protein hydrolase, acylamino-acid-releasing enzyme, acylaminoacyl peptidase, Acylaminoacyl-peptidase, acylpeptide hydrolase, acylpeptide hydrolase/esterase, alpha-N-acylpeptide hydrolase, ApAAP, apAPH, APEH, APEH-1, apeH-2, APEH-3, APEH-3Ss, APEHs, APE_1547.1, APH, APHdr, AtAARE, BmAPH, cAARE, DNF15S2 protein, N-acylaminoacyl-peptide hydrolase, N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, OP85, PhAAP, pi-APH, PM hydrolase, PMH, SpAAP, sso2141, SSO2693, ST0779, yuxL

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.19 Omega peptidases
                3.4.19.1 acylaminoacyl-peptidase

Specific Activity

Specific Activity on EC 3.4.19.1 - acylaminoacyl-peptidase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0007
cellular extract, using N-acetyl-L-Leu-4-nitroanilide as substrate, at pH 7.5 and 90°C
0.124
-
recombinant enzyme, after the induction with IPTG, at 8 h of culture in LB medium
0.172
-
recombinant enzyme, after the induction with IPTG, at 18 h of culture in TB medium
10.2
AB009494
substrate: formyl-Ala-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C
105
AB009494
substrate: acetyl-Leu-4-nitroanilide, pH 5.4, 85°C
109.2
-
-
11.7
AB009494
substrate: acetyl-Met-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C
118
AB009494
substrate: acetyl-Ala-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
13
-
with Tyr-Leu as substrate
13.6
AB009494
substrate: acetyl-Ala-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C
1388
AB009494
substrate: formyl-Met-Ala-Ser, pH 5.4, 85°C
1490
-
-
15
AB009494
substrate: acetyl-Tyr-4-nitroanilide, pH 5.4, 85°C, heat-activated enzyme
1513
AB009494
substrate: formyl-Met-Ala, pH 5.4, 85°C, heat-activated enzyme
154
-
with Phe-p-nitroanilide as substrate
17026
AB009494
substrate: formyl-Met-Ala-Ser, pH 5.4, 85°C, heat-activated enzyme
1830
AB009494
substrate: acetyl-Ala-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
186
-
with Ala-beta-naphthylamide as substrate
19
-
with Tyr-Phe as substrate
206
AB009494
substrate: acetyl-Ala-Ala-Ala-Ala, pH 5.4, 85°C
23
-
with Ala-p-nitroanilide as substrate
344
AB009494
substrate: acetyl-Met-Ala, pH 5.4, 85°C
402
AB009494
substrate: formyl-Ala-Ala-Ala, pH 5.4, 85°C
478
AB009494
substrate: acetyl-Ala-Ala, pH 5.4, 85°C
51
AB009494
substrate: acetyl-Ala-4-nitroanilide, pH 5.4, 85°C, heat-activated enzyme
5120
AB009494
substrate: acetyl-Met-Ala, pH 5.4, 85°C, heat-activated enzyme
5363
AB009494
substrate: formyl-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
6.9
AB009494
substrate: acetyl-Ala-4-nitroanilide, pH 5.4, 85°C
66.8
AB009494
substrate: formyl-Met-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
694
AB009494
substrate: formyl-Met-Leu-Gly, pH 5.4, 85°C
7060
AB009494
substrate: acetyl-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
7064
AB009494
substrate: formyl-Met-Leu-Gly, pH 5.4, 85°C, heat-activated enzyme
750
AB009494
substrate: acetyl-Leu-4-nitroanilide, pH 5.4, 85°C, heat-activated enzyme
77
AB009494
substrate: acetyl-Met-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
77.3
AB009494
substrate: formyl-Ala-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C, heat-activated enzyme
9.5
AB009494
substrate: formyl-Met-Ala-Ala-Ala-Ala-Ala, pH 5.4, 85°C
97.2
AB009494
substrate: formyl-Met-Ala, pH 5.4, 85°C
additional information