3.4.19.1: acylaminoacyl-peptidase
This is an abbreviated version!
For detailed information about acylaminoacyl-peptidase, go to the full flat file.
Word Map on EC 3.4.19.1
-
3.4.19.1
-
marrow
-
immunocytochemical
-
oligopeptidase
-
anti-alkaline
-
prolyl
-
immunophenotyping
-
hla-dr
-
smear
-
cryosta
-
phosphatase-anti-alkaline
-
cytospins
-
immunoenzymatic
-
moabs
-
aeropyrum
-
pernix
-
fluorophosphate
-
immunoenzyme
-
immunoalkaline
-
medicine
-
acylase
-
cytocentrifuge
-
analysis
-
drug development
-
synthesis
-
degradation
- 3.4.19.1
- marrow
-
immunocytochemical
-
oligopeptidase
-
anti-alkaline
-
prolyl
-
immunophenotyping
-
hla-dr
-
smear
-
cryosta
-
phosphatase-anti-alkaline
-
cytospins
-
immunoenzymatic
-
moabs
-
aeropyrum
- pernix
- fluorophosphate
-
immunoenzyme
-
immunoalkaline
- medicine
- acylase
-
cytocentrifuge
- analysis
- drug development
- synthesis
- degradation
Reaction
cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide =
Synonyms
AAP, AARE, AARE/OPH, AAREP, AcpH, acyl aminoacyl peptidase, acyl peptide hydrolase, Acyl-peptide hydrolase, acyl-peptide releasing enzyme, acylamino acid-releasing enzyme, acylamino acid-releasing enzyme/oxidized protein hydrolase, acylamino-acid-releasing enzyme, acylaminoacyl peptidase, Acylaminoacyl-peptidase, acylpeptide hydrolase, acylpeptide hydrolase/esterase, alpha-N-acylpeptide hydrolase, ApAAP, apAPH, APEH, APEH-1, apeH-2, APEH-3, APEH-3Ss, APEHs, APE_1547.1, APH, APHdr, AtAARE, BmAPH, cAARE, DNF15S2 protein, N-acylaminoacyl-peptide hydrolase, N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, OP85, PhAAP, pi-APH, PM hydrolase, PMH, SpAAP, sso2141, SSO2693, ST0779, yuxL
ECTree
3.4.19.1 acylaminoacyl-peptidaseAdvanced search results
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Reference on EC 3.4.19.1 - acylaminoacyl-peptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sherriff, R.M.; Broom, M.F.; Chadwick, V.S.
Isolation and purification of N-formylmethionine aminopeptidase from rat intestine
Biochim. Biophys. Acta
1119
275-280
1992
Rattus norvegicus
Kobayashi, K.; Smith, J.A.
Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction
J. Biol. Chem.
262
11435-11445
1987
Rattus norvegicus
Tsunasawa, S.; Imanaka, T.; Nakazawa, T.
Apparent dipeptidyl peptidase activities of acylamino acid-releasing enzymes
J. Biochem.
93
1217-1220
1983
Sus scrofa
Schoenberger, O.L.; Tschesche, H.
N-Acetylalanine aminopeptidase. A new enzyme from human erythrocytes
Hoppe-Seyler's Z. Physiol. Chem.
362
865-873
1981
Homo sapiens
Tsunasawa, S.; Narita, K.; Ogata, K.
Purification and properties of acylamino acid-releasing enzyme from rat liver
J. Biochem.
77
89-102
1975
Escherichia coli, Escherichia coli B / ATCC 11303, Gallus gallus, Oryctolagus cuniculus, Rattus norvegicus
Scaloni, A.; Ingallinella, P.; Andolfo, A.; Jones, W.; Marino, G.; Manning, J.M.
Structural investigations on human erythrocyte acylpeptide hydrolase by mass spectrometric procedures
J. Protein Chem.
18
349-360
1999
Homo sapiens
Jones, W.M.; Scaloni, A.; Manning, J.M.
Acylaminoacyl-peptidase
Methods Enzymol.
244
227-231
1994
Homo sapiens
Farries, T.C.; Auffret, A.D.; Aitken, A.
Enzyme-mediated peptide synthesis using acylpeptide hydrolase
Eur. J. Biochem.
196
687-692
1991
Ovis aries
Raphel, V.; Giardina, T.; Guevel, L.; Perrier, J.; Dupuis, L.; Guo, X.J.; Puigserver, A.
Cloning, sequencing and further characterization of acylpeptide hydrolase from porcine intestinal mucosa
Biochim. Biophys. Acta
1432
371-381
1999
Sus scrofa
Farries, T.C.; Harris, A.; Auffret, A.D.; Aitken, A.
Removal of N-acetyl groups from blocked peptides with acylpeptide hydrolase
Eur. J. Biochem.
196
679-685
1991
Ovis aries
Ishikawa, K.; Ishida, H.; Koyama, Y.; Kawarabayasi, Y.; Kawahara, J.; Matsui, E.; Matsui, I.
Acylamino acid-releasing enzyme from the thermophilic archaeon Pyrococcus horikoshii
J. Biol. Chem.
273
17726-17731
1998
Pyrococcus horikoshii
Scaloni, A.; Jones, W.M.; Barra, D.; Pospischil, M.; Sassa, S.; Popowicz, A.; Manning, L.R.; Schneewind, O.; Manning, J.M.
Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme
J. Biol. Chem.
267
3811-3818
1992
Homo sapiens
Sharma, K.K.; Orthwerth, B.J.
Bovine lens acylpeptide hydrolase. Purification and characterization of a tetrameric enzyme resistant to urea denaturation and proteolytic inactivation
Eur. J. Biochem.
216
631-637
1993
Bos taurus
Scaloni, A.; Barra, D.; Jones, W.M.; Manning, J.M.
Human acylpeptide hydrolase. Studies on its thiol groups and mechanism of action
J. Biol. Chem.
269
15076-15084
1994
Homo sapiens
Sharma, K.K.; Kester, K.
Peptide hydrolysis in lens: role of leucine aminopeptidase, aminopeptidase III, prolyloligopeptidase and acylpeptidehydrolase
Curr. Eye Res.
15
363-369
1996
Bos taurus
Jones, W.M.; Scaloni, A.; Bossa, F.; Popowicz, A.M.; Schneewind, O.; Manning, J.M.
Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities
Proc. Natl. Acad. Sci. USA
88
2194-2198
1991
Homo sapiens
Radhakrishna, G.; Wold, F.
Purification and characterization of an N-acylaminoacyl-peptide hydrolase from rabbit muscle
J. Biol. Chem.
264
11076-11081
1989
Oryctolagus cuniculus
Chongcharoen, K.; Sharma, K.K.
Characterization of trypsin: modified bovine lens acylpeptide hydrolase
Biochem. Biophys. Res. Commun.
247
136-141
1998
Bos taurus
Krishna, R.G.; Wold, F.
Specificity determinants of acylaminoacyl-peptide hydrolase
Protein Sci.
1
582-589
1992
Oryctolagus cuniculus
Raphel, V.; Lupi, N.; Dupuis, L.; Puigserver, A.
The N-acylpeptide hydrolase from porcine intestine: isolation, subcellular localization and comparative hydrolysis of peptide and isopeptide bonds
Biochimie
75
891-897
1993
Sus scrofa
Mitta, M.; Miyagi, M.; Kato, I.; Tsunasawa, S.
Identification of the catalytic triad residues of porcine liver acylamino acid-releasing enzyme
J. Biochem.
123
924-931
1998
Sus scrofa
Miyagi, M.; Sakiyama, F.; Kato, I.; Tsunasawa, S.
Complete covalent structure of porcine liver acylamino acid-releasing enzyme and identification of its active site serine residue
J. Biochem.
118
771-779
1995
Sus scrofa
Feese, M.; Scaloni, A.; Jones, W.M.; Manning, J.M.; Remington, S.J.
Crystallization and preliminary X-ray studies of human erythrocyte acylpeptide hydrolase
J. Mol. Biol.
233
546-549
1993
Homo sapiens
Wang, G.; Gao, R.; Ding, Y.; Yang, H.; Cao, S.; Feng, Y.; Rao, Z.
Crystallization and preliminary crystallographic analysis of acylamino-acid releasing enzyme from the hyperthermophilic archaeon Aeropyrum pernix
Acta Crystallogr. Sect. D
58
1054-1055
2002
Aeropyrum pernix
Yamauchi, Y.; Ejiri, Y.; Toyoda, Y.; Tanaka, K.
Identification and biochemical characterization of plant acylamino acid-releasing enzyme
J. Biochem.
134
251-257
2003
Cucumis sativus, Arabidopsis thaliana (Q84LM4), Arabidopsis thaliana
Senthilkumar, R.; Sharma, K.K.
Effect of chaotropic agents on the structure-function of recombinant acylpeptide hydrolase
J. Protein Chem.
21
323-332
2002
Sus scrofa
Durand, A.; Villard, C.; Giardina, T.; Perrier, J.; Juge, N.; Puigserver, A.
Structural properties of porcine intestine acylpeptide hydrolase
J. Protein Chem.
22
183-191
2003
Sus scrofa
Richards, P.G.; Johnson, M.K.; Ray, D.E.
Identification of acylpeptide hydrolase as a sensitive site for reaction with organophosphorus compounds and a potential target for cognitive enhancing drugs
Mol. Pharmacol.
58
577-583
2000
Sus scrofa
Zhang, H.F.; Zheng, B.S.; Peng, Y.; Lou, Z.Y.; Feng, Y.; Rao, Z.H.
Expression, purification and crystal structure of a truncated acylpeptide hydrolase from Aeropyrum pernix K1
Acta Biochim. Biophys. Sin.
37
613-617
2005
Aeropyrum pernix K1
Wright, H.; Kiss, A.L.; Szeltner, Z.; Polgar, L.; Fueloep, V.
Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase
Acta Crystallogr. Sect. F
F61
942-944
2005
Sus scrofa
Perrier, J.; Durand, A.; Giardina, T.; Puigserver, A.
Catabolism of intracellular N-terminal acetylated proteins: involvement of acylpeptide hydrolase and acylase
Biochimie
87
673-685
2005
Homo sapiens, Rattus norvegicus, Sus scrofa
Kiss, A.L.; Szeltner, Z.; Fueloep, V.; Polgar, L.
His507 of acylaminoacyl peptidase stabilizes the active site conformation, not the catalytic intermediate
FEBS Lett.
571
17-20
2004
Sus scrofa
Wang, Q.; Yang, G.; Liu, Y.; Feng, Y.
Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation
J. Biol. Chem.
281
18618-18625
2006
Aeropyrum pernix (Q9YBQ2)
Bartlam, M.; Wang, G.; Yang, H.; Gao, R.; Zhao, X.; Xie, G.; Cao, S.; Feng, Y.; Rao, Z.
Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1
Structure
12
1481-1488
2004
Aeropyrum pernix (Q9YBQ2)
Quistad, G.B.; Klintenberg, R.; Casida, J.E.
Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants
Toxicol. Sci.
86
291-299
2005
Homo sapiens, Mus musculus
Edosada, C.Y.; Quan, C.; Wiesmann, C.; Tran, T.; Sutherlin, D.; Reynolds, M.; Elliott, J.M.; Raab, H.; Fairbrother, W.; Wolf, B.B.
Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity
J. Biol. Chem.
281
7437-7444
2006
synthetic construct
Nishimura, M.; Ikeda, K.; Sugiyama, M.
Molecular cloning and characterization of gene encoding novel puromycin-inactivating enzyme from blasticidin S-producing Streptomyces morookaensis
J. Biosci. Bioeng.
101
63-69
2006
Streptomyces morookaense, Streptomyces morookaense JCM 4673
Kiss, A.L.; Hornung, B.; Radi, K.; Gengeliczki, Z.; Sztaray, B.; Juhasz, T.; Szeltner, Z.; Harmat, V.; Polgar, L.
The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity
J. Mol. Biol.
368
509-520
2007
Aeropyrum pernix K1 (Q9YBQ2), Aeropyrum pernix K1
Yamin, R.; Bagchi, S.; Hildebrant, R.; Scaloni, A.; Widom, R.L.; Abraham, C.R.
Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide
J. Neurochem.
100
458-467
2007
Homo sapiens
Kiss, A.L.; Pallo, A.; Naray-Szabo, G.; Harmat, V.; Polgar, L.
Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase
J. Struct. Biol.
162
312-323
2008
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix, Aeropyrum pernix K1 (Q9YBQ2)
Pancetti, F.; Olmos, C.; Dagnino-Subiabre, A.; Rozas, C.; Morales, B.
Noncholinesterase effects induced by organophosphate pesticides and their relationship to cognitive processes: implication for the action of acylpeptide hydrolase
J. Toxicol. Environ. Health B Crit. Rev.
10
623-630
2007
Homo sapiens, Sus scrofa
Zhang, Z.; Zheng, B.; Wang, Y.; Chen, Y.; Manco, G.; Feng, Y.
The conserved N-terminal helix of acylpeptide hydrolase from archaeon Aeropyrum pernix K1 is important for its hyperthermophilic activity
Biochim. Biophys. Acta
1784
1176-1183
2008
Aeropyrum pernix K1 (Q9YBQ2), Aeropyrum pernix K1
Szeltner, Z.; Kiss, A.L.; Domokos, K.; Harmat, V.; Naray-Szabo, G.; Polgar, L.
Characterization of a novel acylaminoacyl peptidase with hexameric structure and endopeptidase activity
Biochim. Biophys. Acta
1794
1204-1210
2009
Pyrococcus horikoshii (O58323), Pyrococcus horikoshii
Yang, G.; Bai, A.; Gao, L.; Zhang, Z.; Zheng, B.; Feng, Y.
Glu88 in the non-catalytic domain of acylpeptide hydrolase plays dual roles: charge neutralization for enzymatic activity and formation of salt bridge for thermodynamic stability
Biochim. Biophys. Acta
1794
94-102
2009
Aeropyrum pernix K1 (Q9YBQ2), Aeropyrum pernix K1
Boehme, L.; Baer, J.W.; Hoffmann, T.; Manhart, S.; Ludwig, H.H.; Rosche, F.; Demuth, H.U.
Isoaspartate residues dramatically influence substrate recognition and turnover by proteases
Biol. Chem.
389
1043-1053
2008
Sus scrofa
Olmos, C.; Sandoval, R.; Rozas, C.; Navarro, S.; Wyneken, U.; Zeise, M.; Morales, B.; Pancetti, F.
Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: involvement of acylpeptide hydrolase and alpha(7) nicotinic receptors
Toxicol. Appl. Pharmacol.
238
37-46
2009
Rattus norvegicus
Palmieri, G.; Langella, E.; Gogliettino, M.; Saviano, M.; Pocsfalvi, G.; Rossi, M.
A novel class of protease targets of phosphatidylethanolamine-binding proteins (PEBP): a study of the acylpeptide hydrolase and the PEBP inhibitor from the archaeon Sulfolobus solfataricus
Mol. Biosyst.
6
2498-2507
2010
Saccharolobus solfataricus (Q7LX61), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q7LX61)
Gogliettino, M.; Balestrieri, M.; Cocca, E.; Mucerino, S.; Rossi, M.; Petrillo, M.; Mazzella, E.; Palmieri, G.
Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights
PLoS One
7
e37921
2012
Saccharolobus solfataricus (Q97VD6), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97VD6)
Zhou, X.; Wang, H.; Zhang, Y.; Gao, L.; Feng, Y.
Alteration of substrate specificities of thermophilic alpha/beta hydrolases through domain swapping and domain interface optimization
Acta Biochim. Biophys. Sin.
44
965-973
2012
Aeropyrum pernix (Q9YBQ2)
Li, R.; Zhang, F.; Cao, S.-G.; Xie, G.-Q.; Gao, R.J.
Expression and characterization of a thermostable acyl-peptide releasing enzyme ST0779 from Sulfolobus tokodaii
Chem. Res. Chin. Univ.
28
851-855
2012
Sulfurisphaera tokodaii (Q973W9), Sulfurisphaera tokodaii 7 (Q973W9)
-
Menyhard, D.K.; Kiss-Szeman A.; Tichy-Racs, E.; Hornung, B.; Radi, K.; Szeltner, Z.; Domokos, K., Szamosi, I.; Naray-Szabo, G.; Polgar, L.; Harmat, V.
A self-compartmentalizing hexamer serine protease from Pyrococcus horikoshii: substrate selection achieved through multimerization
J. Biol. Chem.
288
17884-17894
2013
Pyrococcus horikoshii (O58323), Pyrococcus horikoshii DSM 12428 (O58323)
Palmieri, G.; Bergamo, P.; Luini, A.; Ruvo, M.; Gogliettino, M.; Langella, E.; Saviano, M.; Hegde, R.N.; Sandomenico, A.; Rossi, M.
Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation
PLoS One
6
e25888
2011
Saccharolobus solfataricus
Harmat, V.; Domokos, K.; Menyhard, D.K.; Pallo, A.; Szeltner, Z.; Szamosi, I.; Beke-Somfai, T.; Naray-Szabo, G., Polgar, L.
Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase
J. Biol. Chem.
286
1987-1998
2011
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix, Aeropyrum pernix DSM 11879 (Q9YBQ2)
Papaleo, E.; Renzetti, G.
Coupled motions during dynamics reveal a tunnel toward the active site regulated by the N-terminal alpha-helix in an acylaminoacyl peptidase
J. Mol. Graph. Model.
38
226-234
2012
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2)
Liu, C.; Yang, G.; Wu, L.; Tian, G.; Zhang, Z.; Feng, Y.
Switch of substrate specificity of hyperthermophilic acylaminoacyl peptidase by combination of protein and solvent engineering
Protein Cell
2
497-506
2011
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2)
Are, V.; Ghosh, B.; Kumar, A.; Yadav, P.; Bhatnagar, D.; Jamdar, S.; Makde, R.
Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans
Acta Crystallogr. Sect. F
70
1292-1295
2014
Deinococcus radiodurans
Papaleo, E.; Parravicini, F.; Grandori, R.; De Gioia, L.; Brocca, S.
Structural investigation of the cold-adapted acylaminoacyl peptidase from Sporosarcina psychrophila by atomistic simulations and biophysical methods
Biochim. Biophys. Acta
1844
2203-2213
2014
Deinococcus radiodurans
Gogliettino, M.; Riccio, A.; Balestrieri, M.; Cocca, E.; Facchiano, A.; DArco, T.M.; Tesoro, C.; Rossi, M.; Palmieri, G.
A novel class of bifunctional acylpeptide hydrolases--potential role in the antioxidant defense systems of the Antarctic fish Trematomus bernacchii
FEBS J.
281
401-415
2014
Trematomus bernacchii, Trematomus bernacchii (V5QZ74)
Santhoshkumar, P.; Xie, L.; Raju, M.; Reneker, L.; Sharma, K.K.
Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase
J. Biol. Chem.
289
9039-9052
2014
Mus musculus
Sandoval, R.; Navarro, S.; Garcia-Rojo, G.; Calderon, R.; Pedrero, A.; Sandoval, S.; Wyneken, U.; Pancetti, F.
Synaptic localization of acylpeptide hydrolase in adult rat telencephalon
Neurosci. Lett.
520
98-103
2012
Rattus norvegicus
Nakai, A.; Yamauchi, Y.; Sumi, S.; Tanaka, K.
Role of acylamino acid-releasing enzyme/oxidized protein hydrolase in sustaining homeostasis of the cytoplasmic antioxidative system
Planta
236
427-436
2012
Arabidopsis thaliana
Papaleo, E.; Renzetti, G.; Tiberti, M.
Mechanisms of intramolecular communication in a hyperthermophilic acylaminoacyl peptidase: a molecular dynamics investigation
PLoS ONE
7
e35686
2012
Sporosarcina psychrophila
Ishikawa, K.; Ishida, H.; Koyama, Y.; Kawarabayasi, Y.; Kawahara, J.; Matsui, E.; Matsui, I.
Acylamino acid-releasing enzyme from the thermophilic archaeon Pyrococcus horikoshii
J. Biol. Chem.
273
17726-17731
1998
Pyrococcus horikoshii (AB009494), Pyrococcus horikoshii
Menyhard, D.K.; Orgovan, Z.; Szeltner, Z.; Szamosi, I.; Harmat, V.
Catalytically distinct states captured in a crystal lattice the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality
Acta Crystallogr. Sect. D
71
461-472
2015
Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix, Aeropyrum pernix ATCC 700893 (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2), Aeropyrum pernix JCM 9820 (Q9YBQ2), Aeropyrum pernix NBRC 100138 (Q9YBQ2)
Li, R.; Perez, B.; Jian, H.; Jensen, M.M.; Gao, R.; Dong, M.; Glasius, M.; Guo, Z.
Characterization and mechanism insight of accelerated catalytic promiscuity of Sulfolobus tokodaii (ST0779) peptidase for aldol addition reaction
Appl. Microbiol. Biotechnol.
99
9625-9634
2015
Sulfurisphaera tokodaii (Q973W9), Sulfurisphaera tokodaii, Sulfurisphaera tokodaii JCM 10545 (Q973W9), Sulfurisphaera tokodaii 7T (Q973W9)
Liu, D.; Deng, L.; Wang, D.; Li, W.; Gao, R.
"Bridge regions" regulate catalysis and protein stability of acylpeptide hydrolase
Biochem. Eng. J.
145
42-52
2019
Sulfurisphaera tokodaii (Q973W9), Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix ATCC 700893 (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2), Aeropyrum pernix JCM 9820 (Q9YBQ2), Sulfurisphaera tokodaii 7 (Q973W9), Sulfurisphaera tokodaii DSM 16993 (Q973W9), Sulfurisphaera tokodaii JCM 10545 (Q973W9), Aeropyrum pernix NBRC 100138 (Q9YBQ2), Sulfurisphaera tokodaii NBRC 100140 (Q973W9)
-
Yu, X.; Wang, Q.; Zhou, Y.; Gao, R.; Wang, Y.
Cloning and application of a new acylaminoacyl peptidase from Bacillus subtilis 168 for aldol reaction
Chem. J. Chin. Univ.
36
2454-2460
2015
Bacillus subtilis (A8CWI2), Bacillus subtilis 168 (A8CWI2)
-
Zeng, Z.; Rulten, S.; Breslin, C.; Zlatanou, A.; Coulthard, V.; Caldecott, K.
Acylpeptide hydrolase is a component of the cellular response to DNA damage
DNA Repair
58
52-61
2017
Homo sapiens (P13798), Homo sapiens
Brocca, S.; Ferrari, C.; Barbiroli, A.; Pesce, A.; Lotti, M.; Nardini, M.
A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation
FEBS J.
283
4310-4324
2016
Sporosarcina psychrophila (E1VFE0), Sporosarcina psychrophila
Fu, P.; Sun, W.; Zhang, Z.
Molecular cloning, expression and characterization of acylpeptide hydrolase in the silkworm, Bombyx mori
Gene
580
8-16
2016
Bombyx mori (A0A0X9PFK4), Bombyx mori
Yu, X.; Perez, B.; Zhang, Z.; Gao, R.; Guo, Z.
Mining catalytic promiscuity from thermophilic archaea an acyl-peptide releasing enzyme from Sulfolobus tokodaii (ST0779) for nitroaldol reactions
Green Chem.
18
2753-2761
2016
Sulfurisphaera tokodaii (Q973W9), Sulfurisphaera tokodaii 7 (Q973W9), Sulfurisphaera tokodaii DSM 16993 (Q973W9), Sulfurisphaera tokodaii JCM 10545 (Q973W9), Sulfurisphaera tokodaii NBRC 100140 (Q973W9)
-
Jin, H.; Zhou, Z.; Wang, D.; Guan, S.; Han, W.
Molecular dynamics simulations of acylpeptide hydrolase bound to chlorpyrifosmethyl oxon and dichlorvos
Int. J. Mol. Sci.
16
6217-6234
2015
Aeropyrum pernix (Q9YBQ2)
Wang, D.; Jin, H.; Wang, J.; Guan, S.; Zhang, Z.; Han, W.
Exploration of the chlorpyrifos escape pathway from acylpeptide hydrolases using steered molecular dynamics simulations
J. Biomol. Struct. Dyn.
34
749-761
2016
Aeropyrum pernix (Q9YBQ2)
Zhu, J.; Wang, Y.; Li, X.; Han, W.; Zhao, L.
Understanding the interactions of different substrates with wild-type and mutant acylaminoacyl peptidase using molecular dynamics simulations
J. Biomol. Struct. Dyn.
36
4285-4302
2018
Homo sapiens (P13798), Homo sapiens, Aeropyrum pernix (Q9YBQ2), Aeropyrum pernix ATCC 700893 (Q9YBQ2), Aeropyrum pernix DSM 11879 (Q9YBQ2), Aeropyrum pernix JCM 9820 (Q9YBQ2), Aeropyrum pernix NBRC 100138 (Q9YBQ2)
Jin, H.; Zhu, J.; Dong, Y.; Han, W.
Exploring the different ligand escape pathways in acylaminoacyl peptidase by random acceleration and steered molecular dynamics simulations
RSC Adv.
6
10987-10996
2016
Aeropyrum pernix (Q9YBQ2)
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