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3.4.19.1: acylaminoacyl-peptidase

This is an abbreviated version!
For detailed information about acylaminoacyl-peptidase, go to the full flat file.

Word Map on EC 3.4.19.1

Reaction

cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide =

Synonyms

AAP, AARE, AARE/OPH, AAREP, AcpH, acyl aminoacyl peptidase, acyl peptide hydrolase, Acyl-peptide hydrolase, acyl-peptide releasing enzyme, acylamino acid-releasing enzyme, acylamino acid-releasing enzyme/oxidized protein hydrolase, acylamino-acid-releasing enzyme, acylaminoacyl peptidase, Acylaminoacyl-peptidase, acylpeptide hydrolase, acylpeptide hydrolase/esterase, alpha-N-acylpeptide hydrolase, ApAAP, apAPH, APEH, APEH-1, apeH-2, APEH-3, APEH-3Ss, APEHs, APE_1547.1, APH, APHdr, AtAARE, BmAPH, cAARE, DNF15S2 protein, N-acylaminoacyl-peptide hydrolase, N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, OP85, PhAAP, pi-APH, PM hydrolase, PMH, SpAAP, sso2141, SSO2693, ST0779, yuxL

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.19 Omega peptidases
                3.4.19.1 acylaminoacyl-peptidase

KCat KM Value

KCat KM Value on EC 3.4.19.1 - acylaminoacyl-peptidase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.129 - 6347
2-aminobenzoyl-Ala-Leu-Phe-Gln-Gly-Pro-Phe(NO2)-Ala
4.76
acetyl-Ala-4-nitroanilide
37°C, pH 8
4.72
acetyl-Met-7-amido-4-methylcoumarin
50°C, pH 8
17.5
N-acetyl-L-Ala-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C
0.4 - 17.5
N-acetyl-L-alanyl 4-nitroanilide
32.7
N-acetyl-L-Leu-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C
16.8 - 32.7
N-acetyl-L-leucyl 4-nitroanilide
2
N-acetyl-L-Phe-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C
2
N-acetyl-L-phenylalanyl 4-nitroanilide
pH 7.5, 90°C
0.414 - 865
N-acetyl-Phe-2-naphthylamide
0.2
succinyl-AAA-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C
1.3
succinyl-GGF-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C
0.7
Z-GGL-4-nitroanilide
in 25 mM Tris-HCl buffer pH 7.5, at 90°C