3.4.18.1: cathepsin X
This is an abbreviated version!
For detailed information about cathepsin X, go to the full flat file.
Word Map on EC 3.4.18.1
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3.4.18.1
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cathepsins
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papain-like
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procathepsins
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saitoi
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diagnostics
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galactosialidosis
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medicine
- 3.4.18.1
- cathepsins
-
papain-like
-
procathepsins
- saitoi
- diagnostics
-
galactosialidosis
- medicine
Reaction
Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity =
Synonyms
acid carboxypeptidase, cathepsin B2, cathepsin IV, cathepsin P, cathepsin X, cathepsin Z, CATX, CTPZ, CTSX, CTSZ, cysteine-type carboxypeptidase, lysosomal carboxypeptidase B, mopre, PoCtX
ECTree
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Specific Activity
Specific Activity on EC 3.4.18.1 - cathepsin X
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additional information
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at day 8 after 5th lumbar spinal nerve transection, CATX activity increases strongly and highly significant in the lumbar segment (59% compared to sham operated animals, 90% compared to naive)
additional information
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expression and activity of CATX is upregulated in the spinal cord during the development and progression of neuropathic pain in the CNS of the rat 5th lumbar spinal nerve transection model after lesion, the strongest increase in protein content is found in the thoracic segment (87.4%)