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3.4.17.B5: Pyrococcus furiosus carboxypeptidase

This is an abbreviated version!
For detailed information about Pyrococcus furiosus carboxypeptidase, go to the full flat file.

Reaction

broad specificity for neutral, aromatic, polar, and basic C-terminal residues. No activity with N-carboxybenzoyl-Ala-Pro, N-carboxybenzoyl-Ala-Asp, N-carboxybenzoyl-Ala-Gly, N-carboxybenzoyl-Ala-Glu. =

Synonyms

PfuCP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.B5 Pyrococcus furiosus carboxypeptidase

Substrates Products

Substrates Products on EC 3.4.17.B5 - Pyrococcus furiosus carboxypeptidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro + L-phenylalanine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe + L-histidine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His + L-leucine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + L-leucine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu + L-valine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val + L-tyrosine
show the reaction diagram
-
-
-
?
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser + H2O
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr + L-serine
show the reaction diagram
stepwise hydrolysis of up to seven residues from the C-terminus
-
-
?
N-carboxybenzoyl-Ala-Ala + H2O
N-carboxybenzoyl-Ala + L-alanine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Arg + H2O
N-carboxybenzoyl-Ala + L-arginine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Ile + H2O
N-carboxybenzoyl-Ala + L-isoleucine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Leu + H2O
N-carboxybenzoyl-Ala + L-leucine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Lys + H2O
N-carboxybenzoyl-Ala + L-lysine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Met + H2O
N-carboxybenzoyl-Ala + L-methionine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Phe + H2O
N-carboxybenzoyl-Ala + L-phenylalanine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Trp + H2O
N-carboxybenzoyl-Ala + L-tryptophan
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Tyr + H2O
N-carboxybenzoyl-Ala + L-tyrosine
show the reaction diagram
-
-
-
?
N-carboxybenzoyl-Ala-Val + H2O
N-carboxybenzoyl-Ala + L-valine
show the reaction diagram
-
-
-
?
additional information
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