3.4.17.6: alanine carboxypeptidase

This is an abbreviated version!
For detailed information about alanine carboxypeptidase, go to the full flat file.

Reaction

Release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups =

Synonyms

D-Ala carboxypeptidase IB-C, EC 3.4.12.11, N-benzoyl-L-alanine-aminohydrolase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.6 alanine carboxypeptidase

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Results	in table
1	AA Sequence
1	Application
1	CAS Registry Number
20	Inhibitors
3	Ki Value [mM]
3	KM Value [mM]
5	Metals/Ions
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
3	Organism
2	pH Optimum
2	Purification (Commentary)
1	Reaction
1	Reaction Type
3	Reference
3	Specific Activity [micromol/min/mg]
34	Substrates and Products (Substrate)
1	Subunits
3	Synonyms
2	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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of the Enzyme Summary Page.

Substrates Products on EC 3.4.17.6 - alanine carboxypeptidase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

4-amino-4-deoxypteroyl-Ala + H2O

4-amino-4-deoxypteroate + Ala

Soil bacterium

-

-

81311

-

81311

ir

4-aminobenzoyl-Ala + H2O

4-aminobenzoate + Ala

Soil bacterium

-

-

81311

-

81311

ir

4-aminobenzoylalanine + H2O

?

Soil bacterium

-

-

81311

-

-

?

acyl-Ala + H2O

? + Ala

Soil bacterium

-

-

81311

-

81311

ir

Ala-Ala + H2O

Ala + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzoyl-Ala + H2O

benzoate + Ala

2 entries

benzyloxycarbonyl-Ala + H2O

benzyloxy-CHO + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Ala-Ala + H2O

benzyloxycarbonyl-Ala + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Asp-Ala + H2O

benzyloxycarbonyl-Asp + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Ile-Ala + H2O

benzyloxycarbonyl-Ile + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Leu-Ala + H2O

benzyloxycarbonyl-Leu + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Met-Ala + H2O

benzyloxycarbonyl-Met + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Phe-Ala + H2O

benzyloxycarbonyl-Phe + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzyloxycarbonyl-Ser-Ala + H2O

benzyloxycarbonyl-Ser + Ala

Soil bacterium

-

-

81311

-

81311

ir

Glu-Ala + H2O

Glu + Ala

Soil bacterium

-

-

81311

-

81311

ir

Ile-Ala + H2O

Ile + Ala

Soil bacterium

-

-

81311

-

81311

ir

Leu-Ala + H2O

Leu + Ala

Soil bacterium

-

-

81311

-

81311

ir

Met-Ala + H2O

Met + Ala

Soil bacterium

-

-

81311

-

81311

ir

N-benzoyl-Gly-Ala + H2O

N-benzoyl-Gly + Ala

2 entries

N-benzoyl-L-aminobutyric acid + H2O

benzoate + L-aminobutyric acid

2 entries

p-chlorobenzoyl-Ala + H2O

p-chlorobenzoate + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

p-chlorobenzoyl-Gly + H2O

p-chlorobenzoate + Gly

Rhodococcus equi

-

-

81313

-

81313

ir

p-hydroxybenzoyl-Ala + H2O

p-hydroxybenzoate + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

p-methoxybenzoyl-Gly + H2O

p-methoxybenzoate + Gly

Rhodococcus equi

-

-

81313

-

81313

ir

p-methoxyenzoyl-Ala + H2O

p-methoxybenzoate + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

p-nitrobenzoyl-Ala + H2O

p-nitrobenzoate + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

p-nitrobenzoyl-Gly + H2O

p-nitrobenzoate + Gly

Rhodococcus equi

-

-

81313

-

81313

ir

peptidyl-L-alanine + H2O

?

Soil bacterium

-

peptide can be replaced by a variety of pteroyl or acyl groups, absolute specificity for alanine in carboxyl-terminal position

81311

-

-

?

Phe-Ala + H2O

Phe + Ala

Soil bacterium

-

-

81311

-

81311

ir

Ser-Ala + H2O

Ser + Ala

Soil bacterium

-

-

81311

-

81311

ir

Tyr-Ala + H2O

Tyr + Ala

Soil bacterium

-

-

81311

-

81311

ir

benzoyl-Ala + H2O

benzoate + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

benzoyl-Ala + H2O

benzoate + Ala

Soil bacterium

-

-

81311

-

81311

ir

N-benzoyl-Gly-Ala + H2O

N-benzoyl-Gly + Ala

Rhodococcus equi

-

-

81313

-

81313

ir

N-benzoyl-Gly-Ala + H2O

N-benzoyl-Gly + Ala

Soil bacterium

-

-

81311

-

-

?

N-benzoyl-L-aminobutyric acid + H2O

benzoate + L-aminobutyric acid

Rhodococcus equi

-

-

81313

-

81313

ir

N-benzoyl-L-aminobutyric acid + H2O

benzoate + L-aminobutyric acid

Soil bacterium

-

-

81311

-

-

?