3.4.17.3: lysine carboxypeptidase

This is an abbreviated version!
For detailed information about lysine carboxypeptidase, go to the full flat file.

Reaction

Release of a C-terminal basic amino acid, preferentially lysine =

Synonyms

activated thrombin-activable fibrinolysis inhibitor, anaphylatoxin inactivator, Arginine carboxypeptidase, bradykinase, bradykinin-decomposing enzyme, bradykininase, carboxypeptidase B, carboxypeptidase N, carboxypeptidase N1, carboxypeptidase, arginine, CPase N, CPB, CPE, CPN, CPN1, creatine kinase conversion factor, creatinine kinase convertase, EC 3.4.12.7, hippuryllysine hydrolase, kininase I, kininase Ia, peptidyl-L-lysine(-L-arginine) hydrolase, plasma carboxypeptidase, Plasma carboxypeptidase B, proCPB, protaminase, SCPN, TAFI, TAFIa, thrombin-activatable carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.3 lysine carboxypeptidase

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Results	in table
4	Activating Compound
21	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
202	Disease/ Diagnostics
2	Expression
6	General Information
5	General Stability
2	IC50 Value
61	Inhibitors
42	KM Value [mM]
9	Localization
10	Metals/Ions
26	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
52	Organism
1	PDB ID
5	pH Optimum
1	pH Range
10	Posttranslational Modification
8	Purification (Commentary)
1	Reaction
4	Reaction Type
51	Reference
78	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
126	Substrates and Products (Substrate)
13	Subunits
64	Synonyms
4	Temperature Optimum [°C]
6	Temperature Stability [°C]
25	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.17.3 - lysine carboxypeptidase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

activated thrombin-activable fibrinolysis inhibitor

Homo sapiens

-

-

698988

anaphylatoxin inactivator

-

-

-

-

Arginine carboxypeptidase

-

-

-

-

bradykinase

-

-

-

-

bradykinin-decomposing enzyme

-

-

-

-

bradykininase

-

-

-

-

carboxypeptidase B

2 entries

carboxypeptidase N

6 entries

carboxypeptidase N1

Danio rerio

U3JB00

-

755462

carboxypeptidase, arginine

-

-

-

-

CPase N

-

-

-

-

CPB

2 entries

CPE

Phodopus sungorus

-

-

732362

CPN

6 entries

CPN1

3 entries

creatine kinase conversion factor

-

-

-

-

creatinine kinase convertase

-

-

-

-

EC 3.4.12.7

-

-

formerly

-

hippuryllysine hydrolase

-

-

-

-

kininase I

-

-

-

-

kininase Ia

-

-

-

-

peptidyl-L-lysine(-L-arginine) hydrolase

-

-

-

-

plasma carboxypeptidase

2 entries

Plasma carboxypeptidase B

-

-

-

-

proCPB

Mus musculus

-

-

695421, 700246

protaminase

-

-

-

-

SCPN

-

-

-

-

TAFI

Mus musculus

-

-

695421, 700246

TAFIa

Homo sapiens

-

-

698988

thrombin-activatable carboxypeptidase B

Mus musculus

-

-

695421, 700246

thrombin-activatable fibrinolysis inhibitor

Mus musculus

-

-

695421, 700246

thrombin-activatable procarboxypeptidase B

Mus musculus

-

-

695421, 700246

carboxypeptidase B

Homo sapiens

-

-

698988

carboxypeptidase B

Mus musculus

-

-

695421, 700246

carboxypeptidase N

-

-

-

-

carboxypeptidase N

Homo sapiens

-

-

668070, 670291, 731248

carboxypeptidase N

Homo sapiens

P15169

-

698988

carboxypeptidase N

Mus musculus

-

-

668371, 670291, 731670

carboxypeptidase N

Mus musculus

Q9JJN5

-

754517

carboxypeptidase N

Rattus norvegicus

-

-

653143

CPB

Homo sapiens

-

-

698988

CPB

Mus musculus

-

-

695421, 700246

CPN

-

-

-

-

CPN

Homo sapiens

-

-

653008, 653144, 670291, 731248

CPN

Homo sapiens

P15169

-

698988

CPN

Mus musculus

-

-

731670

CPN

Mus musculus

Q9JJN5

-

652673, 754517

CPN

Rattus norvegicus

-

-

653008, 653143

CPN1

Danio rerio

U3JB00

-

755462

CPN1

Mus musculus

-

-

670291

CPN1

Mus musculus

Q9JJN5

-

754517

plasma carboxypeptidase

Homo sapiens

-

-

698988

plasma carboxypeptidase

Mus musculus

-

-

695421, 700246