3.4.17.3: lysine carboxypeptidase

This is an abbreviated version!
For detailed information about lysine carboxypeptidase, go to the full flat file.

Reaction

Release of a C-terminal basic amino acid, preferentially lysine =

Synonyms

activated thrombin-activable fibrinolysis inhibitor, anaphylatoxin inactivator, Arginine carboxypeptidase, bradykinase, bradykinin-decomposing enzyme, bradykininase, carboxypeptidase B, carboxypeptidase N, carboxypeptidase N1, carboxypeptidase, arginine, CPase N, CPB, CPE, CPN, CPN1, creatine kinase conversion factor, creatinine kinase convertase, EC 3.4.12.7, hippuryllysine hydrolase, kininase I, kininase Ia, peptidyl-L-lysine(-L-arginine) hydrolase, plasma carboxypeptidase, Plasma carboxypeptidase B, proCPB, protaminase, SCPN, TAFI, TAFIa, thrombin-activatable carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.3 lysine carboxypeptidase

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Results	in table
4	Activating Compound
21	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
202	Disease/ Diagnostics
2	Expression
6	General Information
5	General Stability
2	IC50 Value
61	Inhibitors
42	KM Value [mM]
9	Localization
10	Metals/Ions
26	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
52	Organism
1	PDB ID
5	pH Optimum
1	pH Range
10	Posttranslational Modification
8	Purification (Commentary)
1	Reaction
4	Reaction Type
51	Reference
78	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
126	Substrates and Products (Substrate)
13	Subunits
64	Synonyms
4	Temperature Optimum [°C]
6	Temperature Stability [°C]
25	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.17.3 - lysine carboxypeptidase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

cloning of the small active subunit

Homo sapiens

-

36407

expression in CHO cells

Rattus norvegicus

-

653143

expression in COS-7 cells

Mus musculus

Q9JJN5

652673

gene structure comparison, DNA and amino acid sequence determination and analysis

2 entries

gene structure comparison, DNA and amino acid sequence determination and analysis

Mus musculus

-

670291

gene structure comparison, DNA and amino acid sequence determination and analysis

Homo sapiens

-

670291