3.4.17.3: lysine carboxypeptidase

This is an abbreviated version!
For detailed information about lysine carboxypeptidase, go to the full flat file.

Reaction

Release of a C-terminal basic amino acid, preferentially lysine =

Synonyms

activated thrombin-activable fibrinolysis inhibitor, anaphylatoxin inactivator, Arginine carboxypeptidase, bradykinase, bradykinin-decomposing enzyme, bradykininase, carboxypeptidase B, carboxypeptidase N, carboxypeptidase N1, carboxypeptidase, arginine, CPase N, CPB, CPE, CPN, CPN1, creatine kinase conversion factor, creatinine kinase convertase, EC 3.4.12.7, hippuryllysine hydrolase, kininase I, kininase Ia, peptidyl-L-lysine(-L-arginine) hydrolase, plasma carboxypeptidase, Plasma carboxypeptidase B, proCPB, protaminase, SCPN, TAFI, TAFIa, thrombin-activatable carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.3 lysine carboxypeptidase

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Results	in table
4	Activating Compound
21	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
202	Disease/ Diagnostics
2	Expression
6	General Information
5	General Stability
2	IC50 Value
61	Inhibitors
42	KM Value [mM]
9	Localization
10	Metals/Ions
26	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
52	Organism
1	PDB ID
5	pH Optimum
1	pH Range
10	Posttranslational Modification
8	Purification (Commentary)
1	Reaction
4	Reaction Type
51	Reference
78	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
126	Substrates and Products (Substrate)
13	Subunits
64	Synonyms
4	Temperature Optimum [°C]
6	Temperature Stability [°C]
25	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 3.4.17.3 - lysine carboxypeptidase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

thrombin-thrombomodulin complex

2 entries

-

additional information

Mus musculus

-

the enzyme expression level is unaffected by lipopolysaccharides

670291

-

thrombin-thrombomodulin complex

Homo sapiens

P15169

on the vascular endothelial surface

698988

-

thrombin-thrombomodulin complex

Mus musculus

-

on the vascular endothelial surface

695421, 700246

-