3.4.17.20: Carboxypeptidase U

This is an abbreviated version!
For detailed information about Carboxypeptidase U, go to the full flat file.

Word Map on EC 3.4.17.20

3.4.17.20

plasminogen

coagulation

clot

fibrinolytic

thrombosis

thrombomodulin

plasmin

fibrinogen

pai-1

bleeding

inhibitor-1

antifibrinolytic

hemostatic

prothrombin

zymogen

venous

anticoagulant

thromboembolism

tissue-type

d-dimers

hypofibrinolysis

profibrinolytic

thrombolytic

thrombin-thrombomodulin

hypercoagulable

procoagulant

c5a

antithrombin

thrombus

prothrombotic

thrombin-antithrombin

thrombin-mediated

coagulopathy

plasmin-antiplasmin

haemostasis

thromboplastin

medicine

antiplasmin

alpha2-antiplasmin

fxiii

metallocarboxypeptidase

anaphylatoxins

molecular biology

pharmacology

plasmin-mediated

thrombophilia

thrombelastography

activator-induced

thrombin-dependent

rfviia

t-pa-induced

thrombin-cleaved

euglobulin

diagnostics

Reaction

release of C-terminal Arg and Lys from a polypeptide =

Synonyms

aCAP, activated thrombin activable fibrinolysis inhibitor, activated thrombin-activable fibrinolysis inhibitor, activated thrombin-activatable fibrinolysis inhibitor, active carboxypeptidase B, active thrombin-activatable fibrinolysis inhibitor, Arginine carboxypeptidase, Carboxypeptidase B, pro-, carboxypeptidase B2, Carboxypeptidase R, carboxypeptidase U, Carboxypeptidase-U, CPB2, CPR, CPU, Plasma carboxypeptidase B, plasma carboxypeptidase U, plasma CPB, plasma procarboxypeptidase B, plasma procarboxypeptidase B-like proenzyme, plasma procarboxypeptidase U, pro-pCPB, Procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U, proCPU, pTAFI, rTAFI, TAFI, TAFIa, TFAI, thrombin activable fibrinolysis inhibitor, thrombin activatable fibrinolysis inhibitor, Thrombin-activable fibrinolysis inhibitor, thrombin-activatable fibrinolysis inhibitor

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.20 Carboxypeptidase U

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Results	in table
30	Activating Compound
9	AA Sequence
26	Application
2	CAS Registry Number
13	Cloned(Commentary)
2	Crystallization (Commentary)
1147	Disease/ Diagnostics
1	Expression
1	General Information
11	General Stability
39	IC50 Value
105	Inhibitors
2	kcat/KM [mM/s]
26	Ki Value [mM]
40	KM Value [mM]
18	Localization
12	Metals/Ions
15	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
102	Organism
24	PDB ID
16	pH Optimum
3	pI Value
40	Posttranslational Modification
41	Protein Variants
22	Purification (Commentary)
7	Reaction
1	Reaction Type
98	Reference
98	Source Tissue
21	Specific Activity [micromol/min/mg]
1	Storage Stability
114	Substrates and Products (Substrate)
16	Subunits
211	Synonyms
13	Temperature Optimum [°C]
42	Temperature Stability [°C]
38	Turnover Number [1/s]

KI Value

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KI Value on EC 3.4.17.20 - Carboxypeptidase U

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0.00008

(R)-2-guanidino-3-mercaptopropanoic acid