3.4.17.18: carboxypeptidase T

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For detailed information about carboxypeptidase T, go to the full flat file.

Word Map on EC 3.4.17.18

3.4.17.18

camptothecin

pressor

topoisomerase

children

pain

carnitine

services

terminology

percept

session

palmitoyltransferase

surgeon

postoperative

sympathetic

physician

demographic

medicare

reimbursement

comorbidities

posttraumatic

bill

irinotecan

topotecan

veterans

outpatient

commission

insurance

neuropsychological

reoperation

psycinfo

physiotherapy

acuminata

readmission

payment

impulsivity

psychotherapy

malonyl-coa

inattention

handgrip

cotrimoxazole

methylphenidate

cholinephosphotransferase

event-related

myoglobinuria

attention-deficit

stroop

icd-9-cm

degradation

marketscan

therapist

payer

Reaction

releases a C-terminal residue, which may be hydrophobic or positively charged =

Synonyms

carboxypeptidase SG, carboxypeptidase T, CPT, metallocarboxypeptidase T

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.18 carboxypeptidase T

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Results	in table
1	Activating Compound
226	AA Sequence
1	Application
1	CAS Registry Number
10	Cloned(Commentary)
7	Crystallization (Commentary)
7	General Stability
10	Inhibitors
14	kcat/KM [mM/s]
1	Ki Value [mM]
46	KM Value [mM]
4	Localization
12	Metals/Ions
9	Molecular Weight [Da]
17	Organism
24	PDB ID
5	pH Optimum
3	pH Range
3	pI Value
21	Protein Variants
11	Purification (Commentary)
1	Reaction
7	Reaction Type
17	Reference
3	Renatured (Commentary)
2	Source Tissue
2	Specific Activity [micromol/min/mg]
36	Substrates and Products (Substrate)
6	Subunits
13	Synonyms
6	Temperature Optimum [°C]
3	Temperature Range [°C]
4	Temperature Stability [°C]
46	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 3.4.17.18 - carboxypeptidase T

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Thermoactinomyces vulgaris

2 h, 50% loss of activity

647268

Thermoactinomyces vulgaris

8 h, 1 mM Ca2+, 20% loss of activity

647268, 647269

Thermoactinomyces vulgaris

10% denatured protein after 2 h at 65°C, 30 mM Tris-HCl pH 9.0, 0.5 M NaCl, 30% glycerol, 2 mM dithiothreitol, 2 mM cysteine, 10 mM CaCl2, rapid denaturing occurs without CaCl2 under the same conditions

670772