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3.4.17.18: carboxypeptidase T

This is an abbreviated version!
For detailed information about carboxypeptidase T, go to the full flat file.

Word Map on EC 3.4.17.18

Reaction

releases a C-terminal residue, which may be hydrophobic or positively charged =

Synonyms

carboxypeptidase SG, carboxypeptidase T, CPT, metallocarboxypeptidase T

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.18 carboxypeptidase T

Application

Application on EC 3.4.17.18 - carboxypeptidase T

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
degradation
reconstruction of the primary specificity pocket of CpT to make it like CpB neither enhances the CpT5 activity with a substrate possessing C-terminal Arg, nor lowers the activity with a substrate carrying C-terminal Leu. Notwithstanding the considerable structural similarity of CpT and CpB, the mechanisms underlying their substrate specificities are different