3.4.17.17: tubulinyl-Tyr carboxypeptidase

This is an abbreviated version, for detailed information about tubulinyl-Tyr carboxypeptidase, go to the full flat file.

Reaction

Cleavage of the -Glu!Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr =

Synonyms

AGBL4, brain I carboxypeptidase, carboxypeptidase, tubulin-tyrosine, carboxypeptidase-tubulin, MAP1B, microtubule-associated protein 1B, nervous system nuclear protein induced by axotomy, Nna1-like peptidase, soluble carboxypeptidase, TCP, TTCPase, tubulin carboxypeptidase, tubulin-tyrosine carboxypeptidase, tubulinyltyrosine carboxypeptidase, tyrosinotubulin carboxypeptidase, tyrosyltubulin carboxypeptidase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.17 tubulinyl-Tyr carboxypeptidase