3.4.17.15: carboxypeptidase A2

This is an abbreviated version!
For detailed information about carboxypeptidase A2, go to the full flat file.

Reaction

Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues =

Synonyms

ADA2, carboxypeptidase-A2, CP-A2, CPA2

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.15 carboxypeptidase A2

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Results	in table
2	Activating Compound
12	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
1	Crystallization (Commentary)
5	Disease/ Diagnostics
1	General Stability
4	Inhibitors
16	KM Value [mM]
2	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
12	Organism
2	PDB ID
2	pH Optimum
1	pI Value
7	Posttranslational Modification
1	Protein Variants
5	Purification (Commentary)
3	Reaction
1	Reaction Type
12	Reference
1	Renatured (Commentary)
14	Source Tissue
3	Specific Activity [micromol/min/mg]
23	Substrates and Products (Substrate)
4	Subunits
9	Synonyms
1	Temperature Optimum [°C]
2	Temperature Stability [°C]
14	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.17.15 - carboxypeptidase A2

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Rattus norvegicus

-

586913

DNA and amino acid sequence determination and analysis of the preproenzyme, phylogenetic analysis

Paralichthys olivaceus

Q8AXN5

668310

DNA and amino acid sequence determination and analysis, expression of the pro-CPA2 in Saccharomyces cerevisiae

Homo sapiens

-

667298

DNA and amino acid sequence determination and analysis, genetic structure, chromosomal localization at 7q32, quantitative expression analysis, low expression level in genomic regions associated with Silver-Russell syndrome disease, overview

Homo sapiens

-

669813

overexpression of the proenzyme in Pichia pastoris

Homo sapiens

-

669188

procarboxypeptidase A2 is expressed in Pichia pastoris

Homo sapiens

-

647257