3.4.17.14: Zinc D-Ala-D-Ala carboxypeptidase
This is an abbreviated version!
For detailed information about Zinc D-Ala-D-Ala carboxypeptidase, go to the full flat file.
Word Map on EC 3.4.17.14
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3.4.17.14
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peptidoglycan
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beta-lactams
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exocellular
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benzylpenicillin
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muropeptide
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actinomadura
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dd-peptidase
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penicillin-sensitive
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dd-cpases
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murein
-
dd-endopeptidase
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transpeptidation
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ld-carboxypeptidase
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genapol
-
peptidoglycan-mimetic
-
bocillin
-
homari
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zn2+-containing
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gaffkya
- 3.4.17.14
- peptidoglycan
- beta-lactams
-
exocellular
- benzylpenicillin
-
muropeptide
- actinomadura
- dd-peptidase
-
penicillin-sensitive
- dd-cpases
- murein
-
dd-endopeptidase
-
transpeptidation
- ld-carboxypeptidase
-
genapol
-
peptidoglycan-mimetic
-
bocillin
- homari
-
zn2+-containing
-
gaffkya
Reaction
cleavage of the bond: (Ac)2-L-lysyl-D-alanyl-/-D-alanine =
Synonyms
D-alanyl-D-alanine carboxypeptidase, D-Alanyl-D-alanine hydrolase, D-Alanyl-D-alanine-cleaving carboxypeptidase, DAP, DD-Carboxypeptidase, DD-Carboxypeptidase-transpeptidase, G enzyme, KM endopeptidase, More, PBP4, PBP4a, PBP4B, penicillin binding protein 4, penicillin-binding protein 4a, zinc D-Ala-D-Ala carboxypeptidase, Zn2+ G peptidase
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Reference
Reference on EC 3.4.17.14 - Zinc D-Ala-D-Ala carboxypeptidase
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Joris, B.; van Beeumen, J.; Casagrande, F.; Gerday, C.; Frere, J.M.; Ghuysen, J.M.
The complete amino acid sequence of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of streptomyces albus G
Eur. J. Biochem.
130
53-69
1983
Streptomyces albus
Dideberg, O.; Charlier, P.; Dive, G.; Joris, B.; Frere, J.M.; Ghuysen, J.M.
Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution
Nature
299
469-470
1982
Streptomyces albus
Dideberg, O.; Joris, B.; Frere, J.M.; Ghuysen, J.M.; Weber, G.; Robaye, R.; Delbrouck, J.M.; Roelandts, I.
The exocellular DD-carboxypeptidase of Streptomyces albus G: a metallo (Zn2+) enzyme
FEBS Lett.
117
215-218
1980
Streptomyces albus
Frere, J.M.; Moreno, R.; Ghuysen, J.M.; Perkins, H.R.; Dierickx, L.; Delcambe, L.
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39
Biochem. J.
143
233-240
1974
Streptomyces sp.
Kikuchi, H.; Kim, S.; Watanabe, K.; Watarai, M.
Brucella abortus d-alanyl-d-alanine carboxypeptidase contributes to its intracellular replication and resistance against nitric oxide
FEMS Microbiol. Lett.
259
120-125
2006
Brucella abortus
Ghuysen, J.
Zinc D-Ala-D-Ala carboxypeptidase (Streptomyces)
Handbook of Proteolytic Enzymes (Barrett,A. J. ;Rawlings,N. D. ,Woessner)
1
857-858
2004
Streptomyces albus G
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Vega, D.; Ayala, J.A.
The DD-carboxypeptidase activity encoded by pbp4B is not essential for the cell growth of Escherichia coli
Arch. Microbiol.
185
23-27
2006
Escherichia coli
Kishida, H.; Unzai, S.; Roper, D.I.; Lloyd, A.; Park, S.Y.; Tame, J.R.
Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics
Biochemistry
45
783-792
2006
Escherichia coli (P24228), Escherichia coli
Sauvage, E.; Duez, C.; Herman, R.; Kerff, F.; Petrella, S.; Anderson, J.W.; Adediran, S.A.; Pratt, R.F.; Frere, J.M.; Charlier, P.
Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide
J. Mol. Biol.
371
528-539
2007
Bacillus subtilis
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