3.4.17.13: Muramoyltetrapeptide carboxypeptidase

This is an abbreviated version!
For detailed information about Muramoyltetrapeptide carboxypeptidase, go to the full flat file.

Word Map on EC 3.4.17.13

3.4.17.13

peptidoglycan

murein

dd-carboxypeptidase

homari

gaffkya

muropeptide

sacculus

transpeptidation

sphaericus

udp-murnac-tetrapeptide

meso-diaminopimelic

Reaction

hydrolysis of the bond: N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-Ala-D-glutamyl-6-carboxy-L-lysyl-/-D-alanine =

Synonyms

Carboxypeptidase II, Carboxypeptidase IIW, Carboxypeptidase, lysyl-D-alanine, Carboxypeptidase, muramoyltetrapeptide, cjj81176_0915, DacB, L,D-carboxypeptidase A, L-Lysyl-D-alanine carboxypeptidase, LD-Carboxypeptidase, LdcA, LdcA1, LdcA2, LdcB, muramoyltetrapeptide carboxypeptidase, peptidase U61, Pgp2, Spr0554

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.13 Muramoyltetrapeptide carboxypeptidase

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Results	in table
3126	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
3	Crystallization (Commentary)
1	Expression
3	General Information
23	Inhibitors
6	KM Value [mM]
4	Localization
6	Metals/Ions
11	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
80	Organism
4	Pathway
21	PDB ID
7	pH Optimum
1	pH Range
6	Protein Variants
5	Purification (Commentary)
2	Reaction
4	Reaction Type
26	Reference
4	Source Tissue
5	Specific Activity [micromol/min/mg]
1	Storage Stability
47	Substrates and Products (Substrate)
8	Subunits
35	Synonyms
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.4.17.13 - Muramoyltetrapeptide carboxypeptidase

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(3Z)-3-[(3-ethoxypropyl)imino]-N,N-diethyl-3H-1,2,4-dithiazol-5-amine

Escherichia coli

i.e. DTZ, a dithiazoline inhibitor, specificity, overview, the compound has slight antibacterial activity against strain MG1655

Azthreonam

Ca2+

10 mM

D-Amino acids

EDTA

Streptococcus pneumoniae

Q8DQQ1

isoform LcdB is inactive in the presence of EDTA

iodoacetamide

Mg2+

Mn2+

10 mM

NEM

weak

nocardicin A

penicillin G

Thienamycin

Zn2+

additional information

2 entries