3.4.17.10: carboxypeptidase E

This is an abbreviated version!
For detailed information about carboxypeptidase E, go to the full flat file.

Word Map on EC 3.4.17.10

3.4.17.10

cytopathic

carbapenemase-producing

enterobacteriaceae

clostridium

perfringens

enterotoxin

viruses

carbapenemase

pneumonia

electrode

klebsiella

neuropeptides

cloud

outbreak

preconcentration

carriage

swab

enterobacterales

cytopathogenic

carba

meropenem

voltammetric

polyelectrolyte

carbapenem-resistant

cardiogenic

blaoxa-48

colistin

oxa-48-like

alpha-amidating

esbls

enteroviruses

imipenem

vim

ertapenem

proinsulin

antibiotic-associated

claudin-4

blakpc

tcid50

blandm

extended-spectrum

kpc-producing

medicine

spiritual

diagnostics

blaimp

esbl-producing

parapneumonic

hodge

eucast

biotechnology

drug development

macconkey

stewardship

Reaction

release of C-terminal arginine or lysine residues from polypeptides =

Synonyms

carboxypeptidase, carboxypeptidase E, carboxypeptidase E-DELTAN, carboxypeptidase E/H, carboxypeptidase H, carboxypeptidase, enkephalin precursor, Ci-CPE, cobalt stimulated chromaffin granule carboxypeptidase, CPE, CPE-DELTAN, CPE-NFalpha1, CPH, EGL-21, enkephalin convertase, enkephalin precursor carboxypeptidase, enkephalin-precursor endopeptidase, hCPE, insulin granule-associated carboxypeptidase, MCP, membrane-bound carboxypeptidase, metallocarboxypeptidase, More, neurotrophic factor-alpha1, peptidyl-L-lysine(-L-arginine) hydrolase, Prohormone processing carboxypeptidase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.10 carboxypeptidase E

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Results	in table
2	Activating Compound
509	AA Sequence
10	Application
1	CAS Registry Number
18	Cloned(Commentary)
1	Crystallization (Commentary)
3035	Disease/ Diagnostics
4	Expression
26	General Information
84	Inhibitors
16	KM Value [mM]
55	Localization
26	Metals/Ions
10	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
220	Organism
15	pH Optimum
8	pH Range
6	pI Value
14	Posttranslational Modification
11	Protein Variants
12	Purification (Commentary)
1	Reaction
14	Reaction Type
81	Reference
117	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
100	Substrates and Products (Substrate)
10	Subunits
100	Synonyms
5	Temperature Optimum [°C]
3	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.4.17.10 - carboxypeptidase E

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1,10-phenanthroline

8 entries

2-mercaptomethyl-3-guanidinoethylthiopropanoic acid

Aplysia californica

81304

4-Chloromercuriphenylsulfonate

Bos taurus

over 95% inhibition at 0.1 mM

668816

Aminopropylmercapto succinic acid

arginine

CdCl2

CuCl2

EDTA

FeSO4

Guanidinoethylmercaptosuccinic acid

7 entries

HgCl2

6 entries

Leu-enkephalin

2 entries

Luteinizing hormone-releasing hormone

lysine

Met-enkephalin

Met-Enkephalin-Arg-Gly-Leu

2 entries

Met-Enkephalin-Arg6-Phe7

2 entries

Oxytoxin

2 entries

p-chloromercuriphenyl sulfonate

3 entries

Substance P

2 entries

sulfhydryl reagents

2 entries

thyrotropin-releasing hormone

2 entries

Vasopressin

2 entries

[Leu5]Enkephalin-Arg6

Bos taurus

81298, 81299

[Leu5]Enkephalin-Lys6

Bos taurus

81298

[Met5]Enkephalin-Arg6

Bos taurus

81298, 81299

[Met5]Enkephalin-Lys6

Bos taurus

81298, 81299

additional information

Mus musculus

excessive secretogranin III leads to a decrease in CPE-bound proopiomelanocortin-derived intermediate molecules

669586