3.4.15.1: peptidyl-dipeptidase A

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For detailed information about peptidyl-dipeptidase A, go to the full flat file.

Word Map on EC 3.4.15.1

3.4.15.1

hypertension

blocker

cardiovascular

arterial

antihypertensive

cardiac

renin-angiotensin

ventricular

myocardial

captopril

systolic

diuretic

coronary

renin

aceis

infarction

beta-blockers

enalapril

glomerular

diastolic

ejection

proteinuria

mellitus

placebo

hypertrophy

aldosterone

nephropathy

creatinine

hemodynamic

bradykinin

congestive

ras

vasodilator

normotensive

statin

renin-angiotensin-aldosterone

hg

sarcoidosis

losartan

aspirin

prescript

double-blind

angiotensinogen

renoprotective

pressor

digoxin

all-cause

renovascular

microalbuminuria

hypotensive

drug development

veterinary medicine

medicine

Reaction

release of a C-terminal dipeptide, oligopeptide-/-Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II =

Synonyms

ACE, ACE-1, ACE2, ACEI, ANCE, ANG I-converting enzyme, angiotensin 1 converting enzyme, angiotensin converting enzyme, angiotensin converting enzyme 1, angiotensin converting enzyme I, angiotensin converting enzyme inhibitor, angiotensin I converting enzyme, angiotensin I-converting enzyme, angiotensin-converting enzyme, angiotensin-converting enzyme 2, angiotensin-converting enzyme type 1, angiotensin-converting enzyme-2, angiotensin-converting-enzyme, angiotensin-I converting enzyme, angiotensin-I-converting enzyme, carboxycathepsin, carboxypeptidase, dipeptidyl, CD143, CD143 antigen, crab-ACE, DCP, Dcp1, Dipeptidyl carboxypeptidase, dipeptidyl carboxypeptidase I, dipeptidylcarboxypeptidase, endothelial cell peptidyl dipeptidase, gACE, germinal ACE, kinases II peptidyldipeptide hydrolase, kininase II, mACE2, More, PDH, peptidase P, peptidyl dipeptidase, peptidyl dipeptidase A, peptidyl dipeptidase I, peptidyl dipeptidase-4, peptidyl dipeptide hydrolase, peptidyl-dipeptide hydrolase, peptidyldipeptide hydrolase, rhACE2, s-ACE, sACE, sACE-1, somatic ACE, somatic angiotensin I-converting enzyme, TACE, testicular ACE, testis ACE, XcACE, zinc dipeptidyl carboxypeptidase, Zn2+ peptidyldipeptidase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.15 Peptidyl-dipeptidases

3.4.15.1 peptidyl-dipeptidase A

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Results	in table
30	Activating Compound
189	AA Sequence
65	Application
1	CAS Registry Number
25	Cloned(Commentary)
12	Crystallization (Commentary)
65670	Disease/ Diagnostics
2	Expression
54	General Information
3	General Stability
411	IC50 Value
1153	Inhibitors
1	kcat/KM [mM/s]
307	Ki Value [mM]
249	KM Value [mM]
51	Localization
68	Metals/Ions
81	Molecular Weight [Da]
98	Natural Substrates/ Products (Substrates)
739	Organism
132	PDB ID
54	pH Optimum
8	pH Range
3	pH Stability
3	pI Value
49	Posttranslational Modification
39	Protein Variants
51	Purification (Commentary)
1	Reaction
1	Reaction Type
407	Reference
429	Source Tissue
45	Specific Activity [micromol/min/mg]
6	Storage Stability
535	Substrates and Products (Substrate)
56	Subunits
338	Synonyms
37	Temperature Optimum [°C]
1	Temperature Range [°C]
17	Temperature Stability [°C]
172	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.15.1 - peptidyl-dipeptidase A

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ACE

ACE-1

ACE2

ACEI

ANCE

ANG I-converting enzyme

2 entries

angiotensin 1 converting enzyme

angiotensin converting enzyme

6 entries

angiotensin converting enzyme 1

Rattus norvegicus

699747

angiotensin converting enzyme I

Oryctolagus cuniculus

698425

angiotensin converting enzyme inhibitor