Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.14.2: dipeptidyl-peptidase II

This is an abbreviated version!
For detailed information about dipeptidyl-peptidase II, go to the full flat file.

Word Map on EC 3.4.14.2

Reaction

release of an N-terminal dipeptide, Xaa-Yaa-/-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides =

Synonyms

brain dipeptidyl aminopeptidase A, carboxytripeptidase, dipeptidyl aminopeptidase II, dipeptidyl arylamidase II, dipeptidyl peptidase, dipeptidyl peptidase 2, dipeptidyl peptidase II, dipeptidyl-aminopeptidase II, dipeptidylpeptidase II, DP II, DPP, DPP II, DPP-II, DPP2, DPP7, DPPII, DPPV, fibroblast activation protein alpha, GPA, More, peptidase, dipeptidyl, II, QPP, quiescent cell proline dipeptidase, seprase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases
                3.4.14.2 dipeptidyl-peptidase II

pH Range

pH Range on EC 3.4.14.2 - dipeptidyl-peptidase II

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2.5 - 11.5
-
-
3.5 - 8.5
-
3.7 - 5.8
-
pH 3.5: about 85% of maximal activity, pH 5.8: about 45% of maximal activity
4 - 6
pH 4.0: about 50% of maximal activity, pH 6.0: about 40% of maximal activity, substrate: Lys-Ala-p-nitroanilide or Ala-Pro-p-nitroanilide
4 - 7
-
50% of maximal activity at pH 4 and 7
5 - 6
5.5 - 7
-
-