3.4.14.1: dipeptidyl-peptidase I

This is an abbreviated version!
For detailed information about dipeptidyl-peptidase I, go to the full flat file.

Reaction

Release of an N-terminal dipeptide, Xaa-Yaa-/-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro =

Synonyms

Cat C, CATC, cathepsin C, cathepsin J, CTSC, DAP I, DDPI, dipeptide arylamidase I, dipeptidyl aminopeptidase I, dipeptidyl peptidase I, dipeptidyl peptidase I/cathepsin C, dipeptidyl transferase, DPAP1, DPAP2, DPP I, DPP-I, DPPI, EC 3.4.4.9, hDPPI, PBANKA_146070, PFL2290w

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases

                3.4.14.1 dipeptidyl-peptidase I

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
13	Activating Compound
958	AA Sequence
9	Application
1	CAS Registry Number
11	Cloned(Commentary)
2	Crystallization (Commentary)
535	Disease/ Diagnostics
2	Expression
10	General Information
1	General Stability
64	IC50 Value
129	Inhibitors
12	kcat/KM [mM/s]
12	Ki Value [mM]
34	KM Value [mM]
21	Localization
18	Metals/Ions
14	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
90	Organism
72	PDB ID
14	pH Optimum
5	pH Range
5	pH Stability
1	pI Value
5	Posttranslational Modification
2	Protein Variants
16	Purification (Commentary)
1	Reaction
4	Reaction Type
90	Reference
100	Source Tissue
6	Specific Activity [micromol/min/mg]
2	Storage Stability
155	Substrates and Products (Substrate)
5	Subunits
65	Synonyms
3	Temperature Optimum [°C]
4	Temperature Stability [°C]
24	Turnover Number [1/s]

Activating Compound

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Activating Compound on EC 3.4.14.1 - dipeptidyl-peptidase I

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Activating Compound Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

beta-mercaptoethylamine

Rattus norvegicus

-

SH compound required, efficient activator at 25 mM

36141

Cys

2 entries

dithioerythritol

2 entries

DL-homocysteine

Rattus norvegicus

-

SH compound required, efficient activator at 25 mM

36141

GSH

Rattus norvegicus

-

SH compound required, efficient activator at 25 mM

36141

mercaptoethanol

Rattus norvegicus

-

SH compound required, efficient activator at 25 mM

36141

mercaptoethylamine

Rattus norvegicus

-

activates

36144

phenol

Bos taurus

-

activates reaction with Gly-Gly-ethyl ester and Gly-Gly-NH2, no effect on reaction with Gly-Phe-NH2

36134

Pyridine

Bos taurus

-

activates reaction with Gly-Gly-ethyl ester and Gly-Gly-NH2, no effect on reaction with Gly-Phe-NH2

36134

sulfhydryl activators

Rattus norvegicus

-

required

36143

-

additional information

2 entries

-

Cys

Rattus norvegicus

-

activates

36144

Cys

Rattus norvegicus

-

L-Cys, SH compound required, efficient activator at 25 mM

36141

dithioerythritol

Capra hircus

-

5 mM, activates

36145

dithioerythritol

Rattus norvegicus

-

SH compound required, efficient activator at 25 mM

36141

additional information

Penaeus monodon

B4XEV1

the temporal expression of cathepsinC mRNA in the hepatopancreas is up-regulated by lipopolysaccharide stimulation and reaches the maximum level at 4 h post-stimulation, and then drops back to the original level gradually

697447

-

additional information

Penaeus monodon

-

the temporal expression of cathepsinC mRNA in the hepatopancreas is up-regulated by lipopolysaccharide stimulation and reaches the maximum level at 4 h post-stimulation, and then drops back to the original level gradually

697447

-