3.4.13.4: Xaa-Arg dipeptidase

This is an abbreviated version!
For detailed information about Xaa-Arg dipeptidase, go to the full flat file.

Reaction

preferential hydrolysis of Xaa-/-Arg, Xaa-/-Lys or Xaa-/-ornithine dipeptides =

Synonyms

aminoacyl-lysine dipeptidase, aminoacyllysine dipeptidase, N2-(4-amino-butyryl)-L-lysine hydrolase, Nalpha-(gamma-aminobutyryl)-lysine hydrolase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.13 Dipeptidases

3.4.13.4 Xaa-Arg dipeptidase

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Results	in table
2	AA Sequence
1	CAS Registry Number
8	Inhibitors
1	KM Value [mM]
3	Metals/Ions
1	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
1	pH Optimum
2	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
3	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
8	Substrates and Products (Substrate)
6	Synonyms

Substrates Products

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Substrates Products on EC 3.4.13.4 - Xaa-Arg dipeptidase

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aminoacyl-L-arginine + H2O

L-arginine + acylamine

Sus scrofa

36078

aminoacyl-L-lysine + H2O

Sus scrofa

36078

aminoacyl-L-lysine + H2O

L-lysine + acylamine

Sus scrofa

36078

aminoacyl-L-ornithine + H2O

L-ornithine + acylamine

Sus scrofa

36078

Nalpha-(gamma-aminobutryryl)-Arg + H2O

4-aminobutyrate + Arg

Sus scrofa

665079

Nalpha-(gamma-aminobutryryl)-Lys + H2O

4-aminobutyrate + Lys

Sus scrofa

36078, 665079

additional information

Sus scrofa

no hydrolysis of: Nepsilon-(gamma-aminobutyryl)-Lys, dipeptides in which the N-alpha-amino group is blocked, dipeptides in which the C-terminus is blocked

665079