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3.4.13.21: dipeptidase E

This is an abbreviated version!
For detailed information about dipeptidase E, go to the full flat file.

Word Map on EC 3.4.13.21

Reaction

dipeptidase E catalyses the hydrolysis of dipeptides Asp-/-Xaa. It does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides =

Synonyms

alpha-aspartyl dipeptidase, Asp-specific dipeptidase, aspartyl dipeptidase, dipeptidase E, PepE, PepE gene product, Salmonella typhimurium, peptidase E

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.13 Dipeptidases
                3.4.13.21 dipeptidase E

Substrates Products

Substrates Products on EC 3.4.13.21 - dipeptidase E

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-Asp-4-nitroanilide + H2O
L-Asp + 4-nitroaniline
show the reaction diagram
L-Asp-beta-Ala + H2O
L-Asp + beta-Ala
show the reaction diagram
-
28% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-Gly + H2O
L-Asp + Gly
show the reaction diagram
-
75% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-Gly-Gly + H2O
?
show the reaction diagram
L-Asp-L-Ala + H2O
L-Asp + L-Ala
show the reaction diagram
-
153% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Asp + H2O
L-Asp + L-Asp
show the reaction diagram
-
49% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-His + H2O
L-Asp + L-His
show the reaction diagram
L-Asp-L-Leu + H2O
L-Asp + L-Leu
show the reaction diagram
L-Asp-L-Lys + H2O
L-Asp + L-Lys
show the reaction diagram
-
168% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Phe + H2O
L-Asp + L-Phe
show the reaction diagram
-
162% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Phe-methyl ester + H2O
L-Asp + L-Phe-methyl ester
show the reaction diagram
-
14% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Phe-NH2 + H2O
L-Asp + L-Phe-NH2
show the reaction diagram
-
37% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Ser + H2O
L-Asp + L-Ser
show the reaction diagram
-
156% of the activity with L-Asp-L-Leu
-
-
?
L-Asp-L-Val + H2O
L-Asp + L-Val
show the reaction diagram
-
94% of the activity with L-Asp-L-Leu
-
-
?
L-isoasparagine + L-phenylalanine methyl ester
N-(L-alpha-L-aspartyl)-L-phenylalanine methyl ester + ?
show the reaction diagram