3.4.13.20: beta-Ala-His dipeptidase

This is an abbreviated version!
For detailed information about beta-Ala-His dipeptidase, go to the full flat file.

Word Map on EC 3.4.13.20

3.4.13.20

carnosine

dipeptide

nephropathy

anserine

homocarnosine

beta-alanyl-l-histidine

l-histidine

bestatin

n-acetylcarnosine

histidine-containing

carcinine

medicine

analysis

synthesis

Reaction

preferential hydrolysis of the beta-Ala-/-His dipeptide (carnosine), and also anserine, Xaa-/-His dipeptides and other dipeptides including homocarnosine =

Synonyms

carnosinase, carnosinase-1, CN1, CN2, CNDP dipeptidase 2, CNDP1, CNDP2, cytosolic non-specific dipeptidase 2, DmpA, EC 3.4.13.13, EC 3.4.13.3, EC 3.4.3.3, serum carnosinase, tissue carnosinase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.13 Dipeptidases

3.4.13.20 beta-Ala-His dipeptidase

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Results	in table
2	Activating Compound
820	AA Sequence
11	Application
1	CAS Registry Number
10	Cloned(Commentary)
4	Crystallization (Commentary)
519	Disease/ Diagnostics
4	General Information
1	General Stability
23	Inhibitors
11	kcat/KM [mM/s]
2	Ki Value [mM]
23	KM Value [mM]
4	Localization
6	Metals/Ions
18	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
76	Organism
4	Pathway
4	PDB ID
10	pH Optimum
2	pH Stability
1	pI Value
7	Posttranslational Modification
22	Protein Variants
8	Purification (Commentary)
1	Reaction
1	Reaction Type
45	Reference
28	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
104	Substrates and Products (Substrate)
11	Subunits
37	Synonyms
7	Temperature Optimum [°C]
6	Temperature Stability [°C]
14	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 3.4.13.20 - beta-Ala-His dipeptidase

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Homo sapiens

up to 8 h the activity remains within 97.5% of the initial value, thereafter the activity decreases slowly

10 min, stable below

10 min, 51% loss of activity

708466

Pseudomonas sp.

Q4R9M3

10 min, complete inactivation

708466