3.4.13.20: beta-Ala-His dipeptidase
This is an abbreviated version!
For detailed information about beta-Ala-His dipeptidase, go to the full flat file.
Word Map on EC 3.4.13.20
-
3.4.13.20
-
carnosine
-
dipeptide
-
nephropathy
-
anserine
-
homocarnosine
-
beta-alanyl-l-histidine
-
l-histidine
-
bestatin
-
n-acetylcarnosine
-
histidine-containing
-
carcinine
-
medicine
-
analysis
-
synthesis
- 3.4.13.20
- carnosine
- dipeptide
- nephropathy
- anserine
- homocarnosine
- beta-alanyl-l-histidine
- l-histidine
- bestatin
-
n-acetylcarnosine
-
histidine-containing
-
carcinine
- medicine
- analysis
- synthesis
Reaction
preferential hydrolysis of the beta-Ala-/-His dipeptide (carnosine), and also anserine, Xaa-/-His dipeptides and other dipeptides including homocarnosine =
Synonyms
carnosinase, carnosinase-1, CN1, CN2, CNDP dipeptidase 2, CNDP1, CNDP2, cytosolic non-specific dipeptidase 2, DmpA, EC 3.4.13.13, EC 3.4.13.3, EC 3.4.3.3, serum carnosinase, tissue carnosinase
ECTree
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KM Value
KM Value on EC 3.4.13.20 - beta-Ala-His dipeptidase
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3
Gly-4-nitroanilide
100 mM Tris/HCl or 50 mM potassium phosphate, pH 8.0, 30°C
0.21
carnosine
-
Vmax: 356 pmol/min/microgram after addition of 0.08 mM homocarnosine
0.7
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM glycine
0.8
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM L-glutamate
0.9
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM glutathione
0.9
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM reduced glutathione
1
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM cysteine
1.1
carnosine
pH 7.0, temperature not specified in the publication, presence of 1 mM N-acetylcysteine