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3.4.13.18: cytosol nonspecific dipeptidase

This is an abbreviated version!
For detailed information about cytosol nonspecific dipeptidase, go to the full flat file.

Word Map on EC 3.4.13.18

Reaction

hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids =

Synonyms

carboxypeptidase of glutamate like-B, CG17337, CNDP2, CPGL, CPGL-B, diglycinase, dipeptidase, glycylglycine, DPP8, DPP8-v3, EC 3.4.13.1, EC 3.4.13.11, EC 3.4.13.13, EC 3.4.13.15, EC 3.4.13.2, EC 3.4.13.3, EC 3.4.13.8, EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.3, EC 3.4.3.6, Gly-Leu hydrolase, glycyl-glycine dipeptidase, glycyl-L-leucine dipeptidase, glycyl-L-leucine hydrolase, glycyl-L-leucine peptidase, glycyl-leucine dipeptidase, glycylleucine dipeptidase, glycylleucine dipeptide hydrolase, glycylleucine hydrolase, glycylleucine peptidase, human cytosolic non-specific dipeptidase, iminodipeptidase, L-amino-acyl-L-amino-acid hydrolase, L-prolylglycine dipeptidase, N2-beta-alanylarginine dipeptidase, non-specific dipeptidase, PepD, Peptidase A, Pro-X dipeptidase, Pro-Xaa dipeptidase, prolinase, prolyl dipeptidase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.13 Dipeptidases
                3.4.13.18 cytosol nonspecific dipeptidase

Activating Compound

Activating Compound on EC 3.4.13.18 - cytosol nonspecific dipeptidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ala
-
prolinase activity in erythrocytes from both the normal control and the patients with prolidase (EC 3.4.13.9) deficiency is activated
D-Leu
-
enhances activity at concentrations below 20 mM
D-methionine
-
enhances activity at 0-20 mM
D-Val
-
enhances activity at concentrations below 50 mM
DTT
-
activates
Gly
-
prolinase activity in erythrocytes from both the normal control and the patients with prolidase (EC 3.4.13.9) deficiency is activated
glycine
-
-
L-alanine
-
-
Mn2+
-
-
Ser
-
prolinase activity in erythrocytes from both the normal control and the patients with prolidase (EC 3.4.13.9) deficiency is activated