3.4.11.B3: Sulfolobus solfataricus aminopeptidase
This is an abbreviated version!
For detailed information about Sulfolobus solfataricus aminopeptidase, go to the full flat file.
Reaction
Preferentially hydrolyzes Xaa-/-Yaa-, in which Xaa is preferentially a non-polar amino acid, L-Ala or L-Leu. When Xaa is L-Phe or a polar amino acid residue like L-Gly or a basic amino acid residue like L-Lys and L-Arg the rates of hydrolysis are lower =
Synonyms
intracellular Sulfolobus aminopeptidase
ECTree
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Substrates Products
Substrates Products on EC 3.4.11.B3 - Sulfolobus solfataricus aminopeptidase
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REACTION DIAGRAM
glycyl 4-nitroanilide + H2O
glycine + 4-nitroaniline
-
11% of the activity compared to L-Leu-4-nitroanilide
-
-
?
L-methionyl 4-nitroanilide + H2O
L-methionine + 4-nitroaniline
about 70% of the activity compared to L-leucyl 4-nitroanilide
-
-
?
L-prolyl 4-nitroanilide + H2O
L-proline + 4-nitroaniline
about 20% of the activity compared to L-leucyl 4-nitroanilide
-
-
?
additional information
?
-
-
no activity with N-acetyl-L-phenylalanine, N-acetyl-L-leucine, N-benzoyl-L-arginine
-
-
?
L-alanine + 4-nitroaniline
-
118% of the activity compared to L-Leu-4-nitroanilide
-
-
?
L-alanyl 4-nitroanilide + H2O
L-alanine + 4-nitroaniline
about 70% of the activity compared to L-leucyl 4-nitroanilide
-
-
?
L-arginine + 4-nitroaniline
-
63% of the activity compared to L-Leu-4-nitroanilide
-
-
?
L-arginyl 4-nitroanilide + H2O
L-arginine + 4-nitroaniline
about 30% of the activity compared to L-leucyl 4-nitroanilide
-
-
?
L-leucine + 4-nitroaniline
-
-
-
-
?
L-leucyl 4-nitroanilide + H2O
L-leucine + 4-nitroaniline
-
-
-
?
L-lysine + 4-nitroaniline
-
15% of the activity compared to L-Leu-4-nitroanilide
-
-
?
L-lysyl 4-nitroanilide + H2O
L-lysine + 4-nitroaniline
about 15% of the activity compared to L-leucyl 4-nitroanilide
-
-
?
L-phenylalanine + 4-nitroaniline
-
62% of the activity compared to L-Leu-4-nitroanilide
-
-
?
L-phenylalanyl 4-nitroanilide + H2O
L-phenylalanine + 4-nitroaniline
about 35% of the activity compared to L-leucyl 4-nitroanilide
-
-
?