3.4.11.5: prolyl aminopeptidase
This is an abbreviated version!
For detailed information about prolyl aminopeptidase, go to the full flat file.
Word Map on EC 3.4.11.5
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3.4.11.5
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women
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cervical
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smear
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cytology
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pulmonary
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artery
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intraepithelial
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colposcopy
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neoplasia
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hypertension
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cervix
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services
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high-risk
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high-grade
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hemodynamic
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mammography
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undetermined
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physician
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low-grade
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demographic
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airway
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attend
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dysplasia
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vaginal
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gynecologic
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bethesda
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insurance
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triage
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apnea
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precancerous
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endocervical
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exam
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hysterectomy
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mammogram
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catheterization
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medicine
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food industry
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atypia
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cytopathology
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industry
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biotechnology
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agriculture
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low-income
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nutrition
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peroxidase-antiperoxidase
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marital
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hpv-positive
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receipt
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polysomnography
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intercourse
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self-efficacy
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medicaid
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sociodemographic
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analysis
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sleepiness
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telephone
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married
- 3.4.11.5
- women
- cervical
-
smear
-
cytology
- pulmonary
- artery
-
intraepithelial
-
colposcopy
- neoplasia
- hypertension
- cervix
-
services
-
high-risk
-
high-grade
-
hemodynamic
-
mammography
-
undetermined
-
physician
-
low-grade
-
demographic
- airway
-
attend
- dysplasia
- vaginal
- gynecologic
-
bethesda
-
insurance
-
triage
- apnea
-
precancerous
- endocervical
-
exam
-
hysterectomy
-
mammogram
-
catheterization
- medicine
- food industry
-
atypia
-
cytopathology
- industry
- biotechnology
- agriculture
-
low-income
- nutrition
-
peroxidase-antiperoxidase
-
marital
-
hpv-positive
-
receipt
-
polysomnography
-
intercourse
-
self-efficacy
-
medicaid
-
sociodemographic
- analysis
- sleepiness
-
telephone
-
married
Reaction
release of N-terminal proline from a peptide =
Synonyms
aminopeptidase P, aminopeptidase, proline, APP, cytosol aminopeptidase V, EC 3.4.1.4, L-proline aminopeptidase, L-prolyl-peptide hydrolase, More, pamA, PAP, PchPiPA, PepI, pepIP, PEPP, Pf S33 proline aminopeptidase, PfPAP, PIP, PiPA, Plasmodium falciparum S33 proline aminopeptidase, Pro-X aminopeptidase, proline aminopeptidase, proline iminopeptidase, proline-specific aminopeptidase, Prolyl aminopeptidase, TaPAP1, TePAP, Tricorn protease interacting factor F1, TsPAP1, X-pro aminopeptidase (Lactococcus)
ECTree
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Inhibitors
Inhibitors on EC 3.4.11.5 - prolyl aminopeptidase
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2-mercaptoethanol
1 mM ZnCl2 and 5 mM beta-mercapthoethanol, respectively, relative activity: 61%
4-(2-aminoethyl)benzenesulfonyl fluoride
85% inhibition at 1 mM
iodoacetamide
slight inhibition at 1 mM, 90% inhibition at 10 mM
N-tosyl-L-phenylalanyl chloromethyl ketone
0.02 mM, relative activity: 69%
diisopropyl fluorophosphate
87% inhibition at 0.1 mM, 94% at 1.0 mM
N-tosyl-L-lysine chloromethyl ketone
1 mM, relative activity: 62%
phenylmethylsulfonyl fluoride
5 mM, 43.4% residual activity
PMSF
72% inhibition at 0.1 mM, 92% at 1.0 mM
ZnCl2
1 mM ZnCl2 + and 5 mM beta-mercapthoethanol, respectively, relative activity: 61%
additional information
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EDTA, Mg2+, or Ca2+ show no or little inhibitory effect
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additional information
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not affected by bestatin, puromycin, reducing agents, chelating agents and cations
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additional information
no inhibition by PMSF, 2-mercaptoethanol, and diethyl dicarbonate
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additional information
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no inhibition by PMSF, 2-mercaptoethanol, and diethyl dicarbonate
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additional information
not inhibitory: dithiothreitol, 2-mercaptoethanol, H2O2
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additional information
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not inhibitory: dithiothreitol, 2-mercaptoethanol, H2O2
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additional information
no inhibition by E64, i.e. trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane, and pepstatin A at 10 mM
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