3.4.11.24: aminopeptidase S

This is an abbreviated version!
For detailed information about aminopeptidase S, go to the full flat file.

Word Map on EC 3.4.11.24

3.4.11.24

aeromonas

calcium-activated

proteolytica

aminopeptidases

phosphonate

double-zinc

aminolysis

septatus

zinc-bound

amino-terminus

biotechnology

analysis

Reaction

release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues =

Synonyms

aminolysin-S, aminopeptidase S, aminopeptidase yscCo-II, AmpS, AP, APCo-II, bacterial leucine aminopeptidase, dinuclear aminopeptidase, dizinc aminopeptidase, double-zinc aminopeptidase, leucine aminopeptidase, M28.003, S9 aminopeptidase, S9AP-St, SAP, SGAP, SGAPase, SSAP, Streptomyces aminopeptidase, Streptomyces dinuclear aminopeptidase, Streptomyces griseus aminopeptidase, Streptomyces griseus leucine aminopeptidase, transaminopeptidase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.11 Aminopeptidases

3.4.11.24 aminopeptidase S

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Results	in table
593	AA Sequence
3	Application
2	CAS Registry Number
11	Cloned(Commentary)
8	Crystallization (Commentary)
1	General Stability
88	Inhibitors
18	kcat/KM [mM/s]
31	Ki Value [mM]
84	KM Value [mM]
7	Localization
44	Metals/Ions
18	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
41	Organism
17	pH Optimum
8	pH Range
2	pI Value
16	Protein Variants
15	Purification (Commentary)
12	Reaction
13	Reaction Type
35	Reference
9	Source Tissue
25	Specific Activity [micromol/min/mg]
2	Storage Stability
175	Substrates and Products (Substrate)
11	Subunits
67	Synonyms
16	Temperature Optimum [°C]
5	Temperature Range [°C]
14	Temperature Stability [°C]
80	Turnover Number [1/s]

KI Value

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KI Value on EC 3.4.11.24 - aminopeptidase S

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0.000011 - 0.00079

amastatin

4 entries

0.0026 - 0.065

bestatin

4 entries

2.31

bis(p-nitrophenyl)phosphate

Streptomyces griseus

P80561

pH 5.0, 30°C

685067

36.6

D-phenylalanine

Streptomyces griseus

pH 8.0, 30°C, in presence of Ca2+

651046

1.1 - 108

fluoride

8 entries

12.4 - 100

L-leucine

4 entries

0.0005 - 0.0055

L-leucine chloromethyl ketone

2 entries

8.7 - 9.1

L-methionine

2 entries

12.7

L-phenylalanine

Streptomyces griseus

pH 8.0, 30°C, in presence of Ca2+

651046

0.0019 - 0.0053

L-phenylalanine chloromethyl ketone

2 entries

10.3

leucine

Streptomyces griseus

P80561

pH 8.0, 30°C

685067

additional information

2 entries